ChemicalBook >제품 카탈로그 >Ensitrelvir

Ensitrelvir

Ensitrelvir 구조식 이미지

카스 번호:: 1471484-62-4

상품명:: Ensitrelvir

동의어(영문):: (E)-1-(2,4,5-trifluorobenzyl)-6-(6-chloro-2-methyl-2H-indazol-5-ylimino)-3-((1-methyl-1H-1,2,4-triazol-3-yl)methyl)-1,3,5-triazinane-2,4-dione;1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-2-(2-benzothiazolyl)-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]ethyl]amino]carbonyl]-3-methylbutyl]-4-methoxy-;YH53;S-217622;N-((S)-1-(((S)-1-(benzo[d]thiazol-2-yl)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methoxy-1H-indole-2-carboxamide

CBNumber:: CB69306536

분자식:: C30H33N5O5S

포뮬러 무게:: 575.68

MOL 파일:: 1471484-62-4.mol

속성

안전

용도

공급 업체 40

Ensitrelvir 속성

밀도: 1.311±0.06 g/cm3(Predicted)

산도 계수 (pKa): 12.74±0.46(Predicted)

안전

Ensitrelvir C화학적 특성, 용도, 생산

Synthesis

The synthesis of S-217622 is as follows:
To a solution of 18 (0.200g, 0.5mmol) in CH2Cl2 (3mL) at 0°C was added TFA/ H2O (10:1, 2mL), and the solution was stirred for 1h. After evaporating the solvent under reduced pressure, the corresponding deprotected lactam residue (0.100g, 0.53mmol) was coupled to the carboxylic acid 14a (0.136g, 0.38mmol) using the coupling agent HBTU (0.147g, 0.38mmol) in the presence of diisopropylethylamine (0.050mL, 0.38mmol) in DMF (3mL) at 0°C. After 5min stirring, the ice bath was removed, and the solution was allowed to stir for 2h under ambient conditions. The solvent was then evaporated under high vacuum, and the residue was dissolved in ethyl acetate (50mL). The organic layer was washed with 5% citric acid (20mL×2), 5% NaHCO3 (20mL×2), and brine (25mL). The solution was dried over Na2SO4, filtered, and evaporated under reduced pressure to give S-217622.
synthesis of S-217622.png

Ensitrelvir 준비 용품 및 원자재

원자재

준비 용품

Ensitrelvir 공급 업체

글로벌( 40)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Jinan Jianfeng Chemical Co., Ltd	0531-88110457; +8615562555968	info@pharmachemm.com	China	225	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Univar Solutions(China) Co., Ltd.	+8615902132654	ivy.zhuang@univarsolutions.com	China	654	58
Senova Technology Co. Ltd.	+86-0755-86703119 +8618503098836	info@senovatech.com	China	350	58
Hebei Duling International Trade Co. LTD	+8617333973358	sales01@hbduling.cn	China	15664	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	19949	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4664	58
Wuhan Biocar Pharmacy Co.，Ltd	13343447621	linkdevil@foxmail.com	China	62	58