2,5-Dibromopyridine
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2,5-Dibromopyridine 속성
- 녹는점
- 92-95 °C (lit.)
- 끓는 점
- 235 °C / 772mmHg
- 밀도
- 2.0383 (rough estimate)
- 굴절률
- 1.5800 (estimate)
- 인화점
- 62℃
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- -1.57±0.10(Predicted)
- 색상
- 거의 흰색 또는 밝은 베이지색에서 갈색까지
- 수용성
- 불용성
- BRN
- 109099
- InChI
- InChI=1S/C5H3Br2N/c6-4-1-2-5(7)8-3-4/h1-3H
- InChIKey
- ZHXUWDPHUQHFOV-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=C(Br)C=C1
- CAS 데이터베이스
- 624-28-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-20/21/22 | ||
| 안전지침서 | 26-37/39-36/37/39-36 | ||
| 유엔번호(UN No.) | UN2811 | ||
| WGK 독일 | 3 | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29333999 |
2,5-Dibromopyridine C화학적 특성, 용도, 생산
화학적 성질
2,5-Dibromopyridine is an off-white crystalline solid. It is insoluble in water but soluble in strong polar organic solvents. It exhibits strong alkalinity.용도
2,5-Dibromopyridine (cas# 624-28-2) is a compound useful in organic synthesis.제조 방법
To synthesize 2,5-dibromopyridine, follow these steps:Add 2-amino-5-bromopyridine (13.0 kg) into a water-cooled solution at 10 °C.
Slowly add 47% aqueous hydrogen bromide (37 L) to the mixture.
Introduce liquid bromine (11 L) into the mixture.
Maintain the reaction temperature below 10 °C.
Prepare a solution of NaNO2 (16.1 kg) and H2O (19 L) and add it dropwise to the mixture while keeping the temperature between 0-5 °C.
Stir the reaction mixture for 30 minutes.
Treat the mixture with a solution of NaOH (28.0 kg) in water (30 L) at a controlled rate below 20-25 °C.
Extract the reaction mixture with diethyl ether (3 × 40 L).
Dry the organic layer with anhydrous Na2SO4.
Remove the desiccant by filtration.
Evaporate the resulting filtrate under reduced pressure to dryness.
Suspend the residue in heptane (10 L).
Collect the target product molecule, 2,5-dibromopyridine, by filtration.
Synthesis method of 2,5-dibromopyridine
2,5-Dibromopyridine 준비 용품 및 원자재
원자재
준비 용품
2-Bromo-5-iodopyridine
5-Bromo-2-pyridinecarboxylic Acid
5-BROMOPYRIDINE-2-CARBONYL CHLORIDE
6-Methoxynicotinaldehyde
2-(5-BROMO-2-PYRIDYLAZO)-5-(DIETHYLAMINO)PHENOL
2-Bromopyridine-5-boronic acid
5-(Trifluoromethyl)pyridine-2-carboxylic acid
5-BROMO-2-(PYRROLIDIN-1-YL)PYRIDINE
6-(1-PYRROLIDINYL)NICOTINALDEHYDE
5-Bromo-3-pyridinecarboxaldehyde
2-Trifluoromethyl-5-bromopyridine
5-Bromo-2-iodopyridine
Torezolid
2,5-Bis(trifluoromethyl)pyridine
2,5-Dibromopyridine 공급 업체
글로벌( 841)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| EAST STAR BIOTECH (SUZHOU) CO., LTD. | +8617706846989 |
marketing@eaststarbio.com | China | 48 | 58 |
| Suzhou Actchem Co., Ltd. | +8618762124502 |
actchem@qq.com | China | 27 | 58 |
| Nanjing New Thinking Chem Co.,Ltd | +8615896017193 |
nanjingxinsi@163.com | China | 217 | 58 |
| Terma Medicare India Pvt.,Ltd | +8613916485955 |
shivshanghai@yahoo.com | India | 132 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 |
sales@myuchem.com | China | 6710 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 16805 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
2,5-Dibromopyridine 관련 검색:
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