장기간 또는 반복 노출되면 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킴
특정 표적장기 독성 - 반복 노출
구분 1
위험
P260, P264, P270, P314, P501
예방조치문구:
P260
분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P264
취급 후에는 손을 철저히 씻으시오.
P264
취급 후에는 손을 철저히 씻으시오.
P270
이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P310
삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P314
불편함을 느끼면 의학적인 조치·조언을 구하시오.
P321
(…) 처치를 하시오.
P330
입을 씻어내시오.
P405
밀봉하여 저장하시오.
P501
...에 내용물 / 용기를 폐기 하시오.
나트륨(2-아미노-3-(4-브로모벤조일)페닐)아세테이트 C화학적 특성, 용도, 생산
개요
Duract was launched in the US as a potent, orally-active, long lasting peripheral
analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and
diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using
Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to
reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo
derivative of Amfenac, this modification increased the duration of analgesic activity
and antiinflammatory potency. It was also free of any CNS, cardiovascular or
autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA
and 25 mg was slightly more potent than 400 mg of Ibuprofen.
화학적 성질
Yellow Solid
용도
Bromfenac is a non-steroidal anti-inflammatory agent.
정의
ChEBI: The sesquihydrate of the sodium salt of bromfenac. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction.
