암포네산
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암포네산 속성
- 녹는점
- >1000 °C
- 끓는 점
- 499℃
- 밀도
- 1.297
- 인화점
- 256℃
- 용해도
- 0.1M NaOH: 가용성
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 3.50±0.20(Predicted)
- 색상
- 노란색
- InChI
- InChI=1S/C18H16N2O3/c1-2-20-11-15(18(22)23)16(21)14-9-8-13(19-17(14)20)10-12-6-4-3-5-7-12/h3-9,11H,2,10H2,1H3,(H,22,23)
- InChIKey
- WHHHJDGNBVQNAU-UHFFFAOYSA-N
- SMILES
- N1(CC)C2C(=CC=C(CC3=CC=CC=C3)N=2)C(=O)C(C(O)=O)=C1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
암포네산 C화학적 특성, 용도, 생산
개요
Amfonelic acid, a derivative of nalidixic acid, was originally developed as a central nervous system stimulant. It is a highly potent nonamphetamine stimulant whose actions are inhibited by reserpine but not by the tyrosine hydroxylase inhibitor, a-methyltyrosine. Additionally, it enhances the impacts of antipsychotic medicines such as haloperidol, trifluoperazine, and spiperone.용도
Amfonelic acid (AFA) is a dopamine reuptake inhibitor, that has marked effects on brain dopamine metabolism but not noradrenaline metabolism. Experiments on rats have shown that AFA treatment completely prevented the effects of methamphetamine on the dopaminergic system, both morphologically and biochemically. Rats are shown to self-administer amfonelic acid in a dose-dependent manner.참고 문헌
The effects of amfonelic acid alone and in combination with naloxone on brain-stimulation reward DOI: 10.1016/0091-3057(89)90069-5Pharmacologic properties and mechanism of action of amfonelic acid DOI: 10.1016/0014-2999(70)90206-2
참고 문헌
[1] P C Waldmeier. “The effects of amfonelic acid on 5-HT metabolism in rat brain.” Journal of Neural Transmission 57 3 (1983): 149–65.암포네산 준비 용품 및 원자재
원자재
준비 용품
암포네산 공급 업체
글로벌( 100)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 |
sales@anbuchem.com | China | 3000 | 58 |
| LY Global chemicals co.,ltd . | +8618939937369 |
info@lychems.cn | China | 969 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18374 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21687 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10247 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 |
info@pbpharm.com | CHINA | 498 | 58 |
암포네산 관련 검색:
날리딕스산 이소아밀아민 디메틸아미노피리딘 2-메틸-5-에틸피리딘
Amfonelic acid
2-Amino-6-methylpyridine
2-Amino-4-methylpyrimidine
2-Amino-3-acetylpyridine
3-FORMYL-6-METHYL-PYRIDINE
3-Pyridinepropanol
5-ACETYL-2-METHYLPYRIDINE
3-PROPIONYLPYRIDINE
2-AMINO-3-ETHYL-6-METHYLPYRIDINE
2-Methylaminopyridine-3-carbaldehyde
2-AMINO-6-ETHYLPYRIDINE
2-Amino-3-pyridinecarboxaldehyde
3-Pyridinepropionic acid
3,6-DIMETHYL-2-PYRIDINAMINE