성장호르몬방출펩티드

성장호르몬방출펩티드 속성

성장호르몬방출펩티드 C화학적 특성, 용도, 생산

개요

Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.

용도

Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.

Biological Functions

Growth hormone releasing peptide (GHRH) is an endocrine hormone produced in the hypothalamus that acts on the receptors (GHRH-R) of the anterior pituitary gland to stimulate the release of growth hormone (GH).  GHRH includes GHRH-2 and GHRH-6, which have slightly different functions.  GHRH-2 is widely used to diagnose patients with growth hormone deficiency (GHD) and is believed to induce not only growth hormone (GH) release, but also adrenocorticotropic hormone (ACTH) release. GHRH-6 is part of a group of synthetic small peptides with potent growth hormone releasing activity, which has cellular and cardioprotective effects and can be used in heart disease treatment research.

Mechanism of action

Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.

부작용

Carpal tunnel syndrome.Increased insulin resistance.
Type 2 diabetes.
Swelling in the arms and legs (edema)
Joint and muscle pain.
For men, enlargement of breast tissue (gynecomastia).
Increased risk of certain cancers.

Physiological effects

Growth hormone releasing peptide (GHRP) is a cyclase inhibitor that blocks the release of endogenous growth hormone.The peptide acts on both igf-i and somatotrophs, with receptor activity in the hypothalamus.GHRP can be used to increase body weight and control obesity.It has been shown to stimulate cell division and inhibit apoptosis in vitro.

Solubility in water

It is recommended to reconstitute the lyophilized growth hormone releasing peptide in sterile 18MΩ-cm H₂O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.

성장호르몬방출펩티드 준비 용품 및 원자재

원자재

준비 용품

성장호르몬방출펩티드 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Jiafan Trading Company Limited	+8615354498258	sales01@jiafan88.com	China	122	58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.	+86-519-85525359 +86-15995072465	sales@xuanmingchem.com	China	893	58
Anko Intermational Trade Limited	+86-18073326374 +86-18073326374	sales@goodpeptides.com	China	59	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3512	58
Huaian Banting Trading Co., Ltd.	+86-15833978697	sales1@bantingpeptide.com	China	85	58
Forest chemical technology	+85295407470	grant@forestchem.freeqiye.com	China	735	58
Chongqing Soarwin Technology Co., Ltd	+86-15790943001 +86-15790943001	crystal@sorawin.cn	China	420	58
Hebei Mujin Biotechnology Co.,Ltd	+86-13288715578 +86-13288715578	sales@hbmojin.com	China	12747	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1015	58
Shandong Huisheng Import & Export Co., Ltd.	+86-13176845580 +86-13176845580	da@zhongda-biotech.com	China	232	58

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