시스-1,2-디클로로에틸렌

시스-1,2-디클로로에틸렌 속성

시스-1,2-디클로로에틸렌 C화학적 특성, 용도, 생산

화학적 성질

clear colorless liquid

용도

cis-1,2-Dichloroethylene (cis-1,2-DCE) is generally used in the preparation of various enediynes for Bergman cyclization. Applications include the synthesis of:

• 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines to prepare corresponding substituted carbazoles.
• (Z)-1-aryl-3-henen-1,5-diynes to obtain the corresponding aryl substituted benzotriazoles.

It is used as a linker to synthesize boron-dipyrromethene (BODIPY)-based photosensitizer for photodynamic therapy (PDT). cis-1,2-DCE can also be used as a precursor to synthesize intermediates of sporolide B.

일반 설명

A clear colorless liquid with an ether-like odor. Flash point 36-39°F. Denser than water and insoluble in water. Vapors heavier than air. Used in the making of perfumes.

공기와 물의 반응

Highly flammable.Slightly soluble in water.

반응 프로필

1,2-DICHLOROETHYLENE and potassium hydroxide forms chloroacetylene, which is explosive and spontaneously flammable in air. CIS-1,2-DICHLOROETHYLENE is highly toxic, Rutledge, p134(1968).

건강위험

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

화재위험

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mildly toxic by ingestion and inhalation. In high concentration it is irritating and narcotic. Has produced liver and kidney injury in experimental animals. Mutation data reported. Sometimes thought to be nonflammable, however, it is a dangerous fire hazard when exposed to heat or flame. Reaction with solid caustic alkalies or their concentrated solutions produces chloracetylene gas, whch ignites spontaneously in air. Reacts violently with N2O4, KOH, Na, NaOH. Moderate explosion hazard in the form of vapor when exposed to flame. Can react vigorously with oxidizing materials. To fight fire, use water spray, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also VINYLIDENE CHLORIDE and CHLORINATED HYDROCARBONS, ALIPHATIC.

잠재적 노출

Primary irritant (w/o allergic reaction). 1,2-Dichloroethylene is used as a solvent for waxes, resins, and acetylcellulose. It is also used in the extraction of rubber, as a refrigerant; in the manufacture of pharmaceuticals and artificial pearls; and in the extraction of oils and fats from fish and meat.

운송 방법

UN1150 Dichloroethylene, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Purify it by careful fractional distillation, followed by passage through neutral activated alumina. Also by shaking with mercury, drying with K2CO3 and distilling from CaSO4. Stabilise it with 0.02% of 2,6-di-tert-butyl-p-cresol. [Beilstein 1 IV 707.]

비 호환성

May form explosive mixture with air. Attacks some plastics, rubber, and coatings. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Gradual decomposition results in hydrochloric acid formation in the presence of ultraviolet light or upon contact with hot metal or other hot surfaces. Reacts with strong bases; potassium hydroxide; difluoromethylene, dihypofluoride, nitrogen tetroxide (explosive); or copper (and its alloys) producing toxic chloroacetylene which is spontaneously flammable on contact with air. Attacks some plastics and coatings.

폐기물 처리

Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≧100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.

시스-1,2-디클로로에틸렌 준비 용품 및 원자재

원자재

준비 용품

시스-1,2-디클로로에틸렌 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10247	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
BEYOND INDUSTRIES (CHINA) LIMITED	+86-21-52699951; +8613917686115	sales@beyondindustriesgroup.com	China	699	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	021-61259108 18621169109	market03@meryer.com	China	40240	62

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