PMPA(NAALAD아제억제제)
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PMPA(NAALAD아제억제제) 속성
- 끓는 점
- 538.8±60.0 °C(Predicted)
- 밀도
- 1.658±0.06 g/cm3(Predicted)
- 저장 조건
- room temp
- 용해도
- Soluble to 100 mM in sterile
- 산도 계수 (pKa)
- 2.06±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 수용성
- 물에 100mM까지 용해됨
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| RTECS 번호 | SA0454800 |
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PMPA(NAALAD아제억제제) C화학적 특성, 용도, 생산
용도
2-(Phosphonomethyl)pentanedioic Acid is a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor, the enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. A posiible target in the treatment of multiple sclerosis and Schizophrenia.생물학적 활성
Highly potent and selective inhibitor of? glutamate carboxypeptidase 2 (GCP II/N-acetylated α -linked dipeptidase/NAALADase) with a K i value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).Biochem/physiol Actions
2-PMPA is a potent and selective inhibitor of Glutamate carboxypeptidase II (GCPII).PMPA(NAALAD아제억제제) 준비 용품 및 원자재
원자재
준비 용품
PMPA(NAALAD아제억제제) 공급 업체
글로벌( 73)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 |
contact@labnetwork.com | China | 19994 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |