드로페리돌, 펜타닐

드로페리돌, 펜타닐
드로페리돌, 펜타닐 구조식 이미지
카스 번호:
548-73-2
한글명:
드로페리돌, 펜타닐
동의어(한글):
드로페리돌,펜타닐
상품명:
DROPERIDOL
동의어(영문):
R 474;r4749;Dridol;Halkan;Inoval;R 4749;Inappin;Inapsin;Innovan;Innovar
CBNumber:
CB9145418
분자식:
C22H22FN3O2
포뮬러 무게:
379.43
MOL 파일:
548-73-2.mol
MSDS 파일:
SDS

드로페리돌, 펜타닐 속성

녹는점
148-149°C
밀도
1.2154 (estimate)
저장 조건
2-8°C
용해도
물에는 거의 녹지 않으며, 디메틸포름아미드와 염화메틸렌에는 잘 녹고, 에탄올에는 거의 녹지 않습니다(96%).
산도 계수 (pKa)
7.64(at 25℃)
색상
옅은 노란색에서 옅은 베이지까지
수용성
4.1mg/L(30℃)
CAS 데이터베이스
548-73-2(CAS DataBase Reference)
EPA
2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro- (548-73-2)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 22
안전지침서 36
유엔번호(UN No.) 3249
WGK 독일 3
RTECS 번호 DE2100000
위험 등급 6.1(b)
포장분류 III
HS 번호 2933995800
유해 물질 데이터 548-73-2(Hazardous Substances Data)
독성 LD50 oral in rat: 750mg/kg
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
NFPA 704
0
1 0

드로페리돌, 펜타닐 C화학적 특성, 용도, 생산

개요

D roperidol is a butyrophenone that has potent antidopaminergic (D2) activity and mild α2-blocking actions. It produces sedation and anxiolysis and is an effective antiemetic. A dverse effects include vasodilatation and hypotension, and at higher doses, dystonic reactions can occur. D roperidol was used for premedication and in neuroleptanaesthesia until reports of death from long QT syndrome led to its withdrawal in 2001. It has recently been reintroduced and licenced at lower doses for prevention of postoperative nausea and vomiting. D roperidol has an onset of 3–10 min after i.v. injection and duration of action of 6–12h. It undergoes hepatic metabolism, but approximately 10% of the drug is excreted unchanged in the urine.

화학적 성질

Pale Yellow Solid

용도

The neuroleptic droperidol possesses antipsychotic, sedative, and antishock action. It potentiates the action of drugs for narcosis. In psychiatric practice, droperidol is used for psychomotor excitement and hallucinations. The principal use of this drug lies in anesthesiology for neuroleptanalgesia in combination with fentanyl. It is used in premedication as well as in surgical operations and post-operational circumstances.

정의

ChEBI: An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeo .

일반 설명

Droperidol, 1-{1-[3-(p-fluorobenzoyl)propyl]-1,2, 3,6-tetrahydro-4-pyridyl}-2-benzimidazolinone(Inapsine), may be used alone as a preanestheticneuroleptic or as an antiemetic. Because of its very shortactingand highly sedating properties, its most frequent useis in combination (Innovar) with the narcotic agent fentanyl(Sublimaze) preanesthetically.

드로페리돌, 펜타닐 준비 용품 및 원자재

원자재

준비 용품


드로페리돌, 펜타닐 공급 업체

글로벌( 226)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Henan Tianfu Chemical Co.,Ltd.
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info@tianfuchem.com China 21689 55
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49391 58
career henan chemical co
+86-0371-86658258 15093356674;
factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23556 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 28557 58
AFINE CHEMICALS LIMITED
0571-85134551 18958018566;
info@afinechem.com China 15377 58
Alfa Chemistry

info@alfa-chemistry.com United States 2344 58
Aston Chemical
13000000000
sales@astonchem.com United States 1634 58

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