ChemicalBook >제품 카탈로그 >RESATORVID

RESATORVID

RESATORVID 구조식 이미지

카스 번호:: 243984-11-4

상품명:: RESATORVID

동의어(영문):: CS-1150;TAK 242;Resatorvi;RESATORVID;TAK-242(Resatorvid);Resatorvid(TAK-242);RESATORVID; TAK242; TAK 242;(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;Ethyl (R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]-1-cyclohexenecarboxylate;ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate

CBNumber:: CB92455670

분자식:: C15H17ClFNO4S

포뮬러 무게:: 361.82

MOL 파일:: 243984-11-4.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 120

RESATORVID 속성

녹는점: 68-69℃

끓는 점: 462.0±55.0 °C(Predicted)

밀도: 1.39

저장 조건: Sealed in dry,Room Temperature

용해도: insoluble in H2O; ≥100.6 mg/mL in EtOH; ≥18.09 mg/mL in DMSO

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 7.08±0.40(Predicted)

안전

위험 및 안전 성명

HS 번호	2935909099

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드

예방조치문구:

NFPA 704

	0
2		0

RESATORVID C화학적 특성, 용도, 생산

일반 설명

A cell-permeable cyclohexenecarboxylate that disrupts TLR4, but not TLR1-3 or TLR5-10, interaction with adaptor molecules TIRAP and TRAM via direct binding to TLR4 intracellular Cys747 residue.Shown to effectively inhibit TLR4-mediated cellular events (IC₅₀ = 1.8, 1.3, and 1.9 nM, respectively, against LPS-induced NO, IL-6, and TNF-α production in murine RAW264.7 macrophages) in vitro and completely prevent LPS- (7 mg/kg, i.p.) induced death in mice (3 mg/kg; i.v.) in vivo. Also available as a 25 mM solution in DMSO (Cat. No. 508336).

Biochem/physiol Actions

Cell permeable: yes

RESATORVID 준비 용품 및 원자재

원자재

준비 용품

RESATORVID 공급 업체

글로벌( 120)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12740	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9634	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58

RESATORVID 관련 검색:

Abiraterone acetate D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE Rapamycin Celastrol Abiraterone 340722-43-2 ethyl 2-(chlorosulfonyl)cyclohex-1-enecarboxylate 1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester 2-(ethoxycarbonyl)cyclohex-1-ene-1-sulfonic acid ethyl 2-Mercaptocyclohex-1-enecarboxylate Ethyl 2-oxocyclohexanecarboxylate Vonoprazan fumarate INK1117 TAK-733 TAK-960 TAK-063 Resatorvid Impurity 6 Resatorvid Impurity 9