Ro 3306

Ro 3306 구조식 이미지
카스 번호:
872573-93-8
상품명:
Ro 3306
동의어(영문):
CS-770;Ro 3306;RO3306;RO 3306;Ro 3306 USP/EP/BP;5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone;(5Z)-5-Quinolin-6-ylmethylene-2-[(thiophen-2-ylmethyl)-amino]-thiazol-4-one;(Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one;4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)-;(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one;2-[[(Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one
CBNumber:
CB92535693
분자식:
C18H13N3OS2
포뮬러 무게:
351.45
MOL 파일:
872573-93-8.mol
MSDS 파일:
SDS

Ro 3306 속성

끓는 점
569.1±60.0 °C(Predicted)
밀도
1.41
저장 조건
2-8°C
용해도
DMSO: 용해성5mg/mL, 투명
산도 계수 (pKa)
3.99±0.10(Predicted)
물리적 상태
가루
색상
흰색에서 밝은 갈색까지
안정성
제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.

안전

WGK 독일 3

Ro 3306 C화학적 특성, 용도, 생산

용도

RO-3306 is an ATP-competitive and selective CDK1 inhibitor used against a diverse panel of human kinases. Used in the treatment of malignant tumors in conjunction with PARP inhibitors.

Biochem/physiol Actions

RO-3306 is a selective ATP-competitive inhibitor of CDK1. It inhibites CDK1 cyclin B1 activity with Ki of 35 nM, nearly 10-fold selectivity relative to CDK2/cyclin E and over 50-fold relative to CDK4/cyclin D. RO-3306 has been used to cause cell cycle arrest at the G2/M boundary.

Ro 3306 준비 용품 및 원자재

원자재

준비 용품


Ro 3306 공급 업체

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