3-Chloropropiophenone
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3-Chloropropiophenone 속성
- 녹는점
- 48-50 °C(lit.)
- 끓는 점
- 113-115 °C4 mm Hg(lit.)
- 밀도
- 1.1115 (rough estimate)
- 굴절률
- 1.5350 (estimate)
- 인화점
- >230 °F
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 황백색에서 연한 노란색
- 수용성
- 불용성
- BRN
- 2043580
- 안정성
- 안정적인. 강염기, 강산화제와 호환되지 않습니다.
- CAS 데이터베이스
- 936-59-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 37/39-26-24/25 | ||
| WGK 독일 | 3 | ||
| TSCA | Yes | ||
| HS 번호 | 29147000 |
3-Chloropropiophenone C화학적 특성, 용도, 생산
개요
3-Chloropropiophenone is a chiral compound that is used as an antidepressant drug. It was first synthesized in the 1950s and has been studied extensively for its pharmacological effects. It is a racemic mixture of two enantiomers, one of which is active and the other inactive. The active enantiomer binds to serotonin receptors and inhibits the reuptake of serotonin, which leads to an increase in serotonin levels. The inactive enantiomer does not bind to serotonin receptors and does not inhibit the reuptake of serotonin. 3-Chloropropiophenone has been shown to be effective when administered at an optimum concentration of 5 milligrams per kilogram body weight.화학적 성질
faintly yellow to tan crystalline powder용도
3-Chloropropiophenone is an Impurity of Fluoxetine (F597100).Synthesis
Adding 3' -chlorobenzene acetone and levorotatory prolinol into 95% ethanol and stirring; cooling after the reaction liquid is wholly dissolved; adding potassium borohydride into the reaction solution in batches, and preserving heat after adding; heating the reaction solution for reflux reaction, and concentrating the reaction solution under reduced pressure; adding n-hexane into the reaction solution, heating, and adding active carbon for heat preservation and decoloration; filtering the reaction solution, leaching a filter cake by using normal hexane, and collecting filtrate; crystallizing and filtering the filtrate, leaching the filter cake once with n-hexane, and drying in vacuum to obtain 3-Chloropropiophenone.3-Chloropropiophenone 준비 용품 및 원자재
원자재
(1R)-3-Chloro-1-phenyl-propan-1-ol
(3-chloroprop-1-ene-1,1-diyl)dibenzene
1-PHENYL-1-CYCLOPROPANOL
3-CHLORO-1-PHENYL-1-PROPANOL
1-Phenyl-2-propen-1-one
Cinnamyl chloride
3-클로로프로피온산 클로라이드
프로피오페논
클로로(3-)프로피온산메틸에스테르
1-Chloro-3-phenylpropane
벤젠
염화벤조일
벤조산에틸에스테르
준비 용품
3-Chloropropiophenone 공급 업체
글로벌( 472)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Lihe Pharm Technology（Wuhan）Co.,Ltd | +8618071517867 |
info@lihepharma.com | China | 194 | 58 |
| Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd. | +86-86-02586819868 +8613913839793 |
sales@jinchemical.com | China | 23 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18223 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 |
sales@sdperfect.com | China | 294 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
| Yantai Fenglu Fine Chemical Co. LTD | +86-+undefined-008618315825527 +86-+undefined-008618315825527 |
kevin.wang@xhtechgroup.com | China | 42 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15956 | 58 |