2'-Deoxy-L-thymidine manufacturers and suppliers

2'-Deoxy-L-thymidine suppliers

Properties

Melting point:: 188-190°C

alpha: D20 -20.3° (c = 0.192 in water)

Density: 1.452±0.06 g/cm3(Predicted)

storage temp.: Sealed in dry,2-8°C

solubility: H2O: soluble10mg/mL (clear solution)

pka: 9.55±0.10(Predicted)

form: powder

color: white to beige

optical activity: [α]/D -15 to -22°, c = 1 in H2O

InChIKey: IQFYYKKMVGJFEH-CSMHCCOUSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P280-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22

Safety Statements: 24/25

WGK Germany: 3

RTECS: UV9048500

HS Code: 29349990

Use

Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.Telbivudine(Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection. Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic 2'-Deoxy-L-thymidine is White Solid

You can find 2'-Deoxy-L-thymidine suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.