PIMOZIDE manufacturers and suppliers

Pimozide suppliers

Properties

Melting point:: 214-218°

Density: 1.1763 (estimate)

storage temp.: 2-8°C

solubility: DMSO: 18 mg/mL

pka: 7.32(at 25℃)

form: White solid

color: Off-White to Light Orange

Water Solubility: 2.9mg/L(30 ºC)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 22

Safety Statements: 36

RIDADR: 3249

WGK Germany: 3

RTECS: DE1750000

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 2933399090

Use

Pimozide, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone (Orap), isa white to creamy white solid (pKa＝9.42). Pimozide is 50%absorbed after oral administration. It is metabolized byCYP450 enzymes, in particular the CYP3A4 and CYP1A2isozymes, to inactive metabolites. Pimozide is excreted in theurine and to a lesser extent in the feces. Toxic effects may beproduced with pimozide in the presence of inducers or inhibitorsof CYP3A4 and CYP1A2. Pimozide is also a stronginhibitor of CYP2D6 without appearing to be an importantsubstrate of this isoform.99 The use of pimozide in the UnitedStates is small, but it is a critical drug for many patients withGilles de la Tourette disorder who cannot tolerate haloperidol.

You can find Pimozide suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.