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ChemicalBook >> CAS DataBase List >> 3-CHLORO-5-HYDROXY-BENZOIC ACID

3-CHLORO-5-HYDROXY-BENZOIC ACID

3-CHLORO-5-HYDROXY-BENZOIC ACID price.
  • $16 - $1460.2
  • Product name: 3-CHLORO-5-HYDROXY-BENZOIC ACID
  • CAS: 53984-36-4
  • MF: C7H5ClO3
  • MW: 172.57
  • EINECS:
  • MDL Number:MFCD04114327
  • Synonyms:3-CHLORO-5-HYDROXY-BENZOIC ACID;5-(hydroxy)-3-chlorobenzoic acid;5-Chloro-m-salicylic Acid;3-chloro-5-hydroxy BA;Benzoic acid, 3-chloro-5-hydroxy-;GPR81 Agonist, 3Cl-5OH-BA ;GPR81 Agonist, 3Cl-5OH-BA - CAS 53984-36-4 - Calbiochem
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  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Atlantic Research Chemicals
  • Biosynth Carbosynth
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  • Chemenu
  • Crysdot
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  • 250mgs:
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberJ97191
  • Product description3-Chloro-5-hydroxybenzoic acid
  • Packaging25g
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number53984364
  • Product description3-Chloro-5-hydroxybenzoic acid
  • Packaging1g
  • Price$1460.2
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging100mg
  • Price$16
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging250mg
  • Price$22
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging1g
  • Price$60
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging5g
  • Price$215
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging10g
  • Price$388
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA125212
  • Product description3-Chloro-5-hydroxybenzoic acid 95+%
  • Packaging25g
  • Price$521
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0142427
  • Product description3-CHLORO-5-HYDROXY-BENZOIC ACID 98.00%
  • Packaging5MG
  • Price$502.12
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC3411
  • Product description3-chloro-5-hydroxyBA
  • Packaging10mM(in 1mL DMSO)
  • Price$42
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC3411
  • Product description3-chloro-5-hydroxyBA
  • Packaging50mg
  • Price$52
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC3411
  • Product description3-chloro-5-hydroxyBA
  • Packaging100mg
  • Price$98
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC3411
  • Product description3-chloro-5-hydroxyBA
  • Packaging500mg
  • Price$425
  • Updated2021-12-16
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  • ManufacturerAtlantic Research Chemicals
  • Product numberCA001244
  • Product description3-Chloro-5-hydroxybenzoic acid 95%
  • Packaging250mgs:
  • Price$35.35
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFC51517
  • Product description3-Chloro-5-hydroxy-benzoic acid
  • Packaging5G
  • Price$112.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFC51517
  • Product description3-Chloro-5-hydroxy-benzoic acid
  • Packaging10g
  • Price$200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J97191 3-Chloro-5-hydroxybenzoic acid 25g $580 2021-12-16 Buy
Alichem 53984364 3-Chloro-5-hydroxybenzoic acid 1g $1460.2 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 100mg $16 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 250mg $22 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 1g $60 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 5g $215 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 10g $388 2021-12-16 Buy
Ambeed A125212 3-Chloro-5-hydroxybenzoic acid 95+% 25g $521 2021-12-16 Buy
American Custom Chemicals Corporation HCH0142427 3-CHLORO-5-HYDROXY-BENZOIC ACID 98.00% 5MG $502.12 2021-12-16 Buy
ApexBio Technology C3411 3-chloro-5-hydroxyBA 10mM(in 1mL DMSO) $42 2021-12-16 Buy
ApexBio Technology C3411 3-chloro-5-hydroxyBA 50mg $52 2021-12-16 Buy
ApexBio Technology C3411 3-chloro-5-hydroxyBA 100mg $98 2021-12-16 Buy
ApexBio Technology C3411 3-chloro-5-hydroxyBA 500mg $425 2021-12-16 Buy
Atlantic Research Chemicals CA001244 3-Chloro-5-hydroxybenzoic acid 95% 250mgs: $35.35 2021-12-16 Buy
Biosynth Carbosynth FC51517 3-Chloro-5-hydroxy-benzoic acid 5G $112.5 2021-12-16 Buy
Biosynth Carbosynth FC51517 3-Chloro-5-hydroxy-benzoic acid 10g $200 2021-12-16 Buy

Properties

Melting point :244.0 to 248.0 °C
Boiling point :364.8±27.0 °C(Predicted)
Density :1.536±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble15mg/mL (clear solution)
form :powder
pka :3.71±0.10(Predicted)
color :white to beige
InChIKey :RJOLIYHZZKAIET-UHFFFAOYSA-N
CAS DataBase Reference :53984-36-4

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GPR81, also known as hydroxycarboxylic acid receptor 1 (HCAR1), is a recently de-orphanized receptor that is activated by lactic acid (EC50 ~ 1.5 mM) but not by other hydroxycarboxylic acids. 3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 = 16 μM) that is inactive against the related GPR109a (HCAR2) receptor. It is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks. 3-chloro-5-hydroxy BA, like lactate, blocks basal ghrelin secretion by primary gastric mucosal cells.

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