KP 103
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- $14 - $2500
- Product name: KP 103
- CAS: 164650-44-6
- MF: C18H22F2N4O
- MW: 348.39
- EINECS:813-597-5
- MDL Number:MFCD00936406
- Synonyms:KP 103;KP 103 (pharmaceutical);(2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)-2-butanol;Efinaconazole(KP 103);(R,R)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)-2-butanol;(αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol;1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βR)-;Efinaconazole (Jublia)
33 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number2856AH
- Product descriptionEfinaconazole
- Packaging25mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging5mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging10mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging25mg
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging50mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging100mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging250mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging1g
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA162236
- Product descriptionEfinaconazole 98+%
- Packaging5g
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024525
- Product descriptionEFINACONAZOLE 95.00%
- Packaging5MG
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4834
- Product descriptionEfinaconazole
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4834
- Product descriptionEfinaconazole
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4834
- Product descriptionEfinaconazole
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4834
- Product descriptionEfinaconazole
- Packaging50mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4834
- Product descriptionEfinaconazole
- Packaging100mg
- Price$1995
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS034495
- Product descriptionEfinaconazole ≥98%
- Packaging250mg
- Price$51
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2856AH | Efinaconazole | 25mg | $96 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 5mg | $14 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 10mg | $17 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 25mg | $21 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 50mg | $27 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 100mg | $34 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 250mg | $52 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 1g | $136 | 2021-12-16 | Buy |
| Ambeed | A162236 | Efinaconazole 98+% | 5g | $410 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024525 | EFINACONAZOLE 95.00% | 5MG | $660 | 2021-12-16 | Buy |
| ApexBio Technology | B4834 | Efinaconazole | 5mg | $55 | 2021-12-16 | Buy |
| ApexBio Technology | B4834 | Efinaconazole | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | B4834 | Efinaconazole | 10mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B4834 | Efinaconazole | 50mg | $210 | 2021-12-16 | Buy |
| ApexBio Technology | B4834 | Efinaconazole | 100mg | $1995 | 2021-12-16 | Buy |
| Arctom | AS034495 | Efinaconazole ≥98% | 250mg | $51 | 2021-12-16 | Buy |
Properties
Melting point :192-195°C
Boiling point :512.2±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.11±0.29(Predicted)
form :powder
color :white to beige
optical activity :[α]/D -85 to -95°, c = 1 in chloroform
Boiling point :512.2±60.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.11±0.29(Predicted)
form :powder
color :white to beige
optical activity :[α]/D -85 to -95°, c = 1 in chloroform
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
In October 2013, efinaconazole (also known as KP-103) was approved in Canada as a 10% topical solution for the treatment of onychomycosis. Like other azole antifungal agents, efinaconazole acts by disrupting fungal cell membranes through inhibition of sterol 14α-demethylase, an enzyme involved in the biosynthesis of ergosterol, which is a key component of the fungal cell membrane. Efinaconazole has potent antifungal activity against clinical isolates of dermatophytes, including Trichophyton mentagrophyes (MIC80 =0.125 μg/mL) and Trichophyton rubrum (MIC80 =0.25 μg/mL), as well as against Candida and Malassezia species. Unlike other antifungal agents, efinaconazole retains activity in the presence of keratin, indicating that more unbound drug is available at the site of action. Efinaconazole is efficacious in guinea-pig models of fungal infection. Efinaconazole is prepared by reaction of an epoxide intermediate with 4-methylenepiperidine.More related product prices
Fluconazole Posaconazole Luliconazole Dutasteride Roflumilast 37025-55-1 NBI 56418NARelated product price
- Fluconazole
$5-1504.5 - Posaconazole
$6-2691.1 - Luliconazole
$8-1172
Suppliers and manufacturers
Jinan Qinmu Fine Chemical Co.,Ltd.
Guangzhou TongYi biochemistry technology Co.,LTD
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
