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ChemicalBook >> CAS DataBase List >> TIC10

TIC10

TIC10 price.
  • $32 - $1400
  • Product name: TIC10
  • CAS: 1616632-77-9
  • MF: C24H26N4O
  • MW: 386.49
  • EINECS:-0
  • MDL Number:MFCD28118993
  • Synonyms:ONC201,TIC10;TIC-10 (ON201);2,4,6,7,8,9-Hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one;TIC10(ONC-201);TIC 10 active isomer;ONC201;7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-on;TIC10
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5389
  • Product descriptionTIC10
  • Packaging100mg
  • Price$1053
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8724
  • Product descriptionONC201
  • Packaging5mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8724
  • Product descriptionONC201
  • Packaging10mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8724
  • Product descriptionONC201
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8724
  • Product descriptionONC201
  • Packaging100mg
  • Price$475
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16109
  • Product descriptionTIC10 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16109
  • Product descriptionTIC10 ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16109
  • Product descriptionTIC10 ≥98%
  • Packaging10mg
  • Price$199
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16109
  • Product descriptionTIC10 ≥98%
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003164
  • Product descriptionTIC10(ONC-201) 98+%
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003164
  • Product descriptionTIC10(ONC-201) 98+%
  • Packaging100mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003164
  • Product descriptionTIC10(ONC-201) 98+%
  • Packaging250mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8868
  • Product descriptionTIC10 >98%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8868
  • Product descriptionTIC10 >98%
  • Packaging1g
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB285480
  • Product description7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one
  • Packaging50mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5389 TIC10 100mg $1053 2021-12-16 Buy
ApexBio Technology A8724 ONC201 5mg $63 2021-12-16 Buy
ApexBio Technology A8724 ONC201 10mg $94 2021-12-16 Buy
ApexBio Technology A8724 ONC201 50mg $300 2021-12-16 Buy
ApexBio Technology A8724 ONC201 100mg $475 2021-12-16 Buy
Cayman Chemical 16109 TIC10 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 16109 TIC10 ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 16109 TIC10 ≥98% 10mg $199 2024-03-01 Buy
Cayman Chemical 16109 TIC10 ≥98% 25mg $420 2024-03-01 Buy
Crysdot CD31003164 TIC10(ONC-201) 98+% 50mg $240 2021-12-16 Buy
Crysdot CD31003164 TIC10(ONC-201) 98+% 100mg $360 2021-12-16 Buy
Crysdot CD31003164 TIC10(ONC-201) 98+% 250mg $520 2021-12-16 Buy
DC Chemicals DC8868 TIC10 >98% 100mg $350 2021-12-16 Buy
DC Chemicals DC8868 TIC10 >98% 1g $1400 2021-12-16 Buy
TRC B285480 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one 50mg $160 2021-12-16 Buy

Properties

Boiling point :559.7±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
pka :6.38±0.20(Predicted)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS):
Signal word:
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Description

TIC10 induces the expression of TNF-related apoptosis-inducing ligand (TRAIL) at 1-5 μM in a p53-independent manner. It is orally active, stable, and crosses the blood-brain barrier. The induction of TRAIL results from dual inhibition of Akt and ERK1/2 combined with nuclear translocation of the transcription factor FOXO3a. TIC10 suppresses the growth of orthotopic human glioblastoma multiforme tumors in mice.

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