| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Cas:2508-72-7
ProductName:Antazoline(hydrochloride)
Brand:Caymanchem | Product Number:23415 | Purity:≥98%
|
- Antazoline
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- $110.00/ kilogram
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2023-12-07
- CAS:154-68-7
- Min. Order: 1kilogram
- Purity: 99%
- Supply Ability: 10 tons/per week
- Antazoline
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- $1.00 / 1g
-
2021-07-20
- CAS:91-75-8
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 50tons
- Antazoline
-
- $1.00 / 1KG
-
2019-09-02
- CAS:91-75-8
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 200kg
|
| | Antazoline Hcl Basic information |
| Product Name: | Antazoline Hcl | | Synonyms: | 2-(n-phenyl-n-benzylaminomethyl)imidazolinehydrochloride;2-phenylbenzylaminomethylimidazolinehydrochloride;antistinehydrochloride;fenazolina;histazine;Antazolin Hcl;2-(N-Benzyl-N-phenylaminonomethyl)-2-imidazoline;N-BENZYL-N-(2-IMIDAZOLIN-2-YLMETHY)ANILINE | | CAS: | 2508-72-7 | | MF: | C17H20ClN3 | | MW: | 301.81 | | EINECS: | 219-719-8 | | Product Categories: | Histamine receptor;2508-72-7 | | Mol File: | 2508-72-7.mol |  |
| | Antazoline Hcl Chemical Properties |
| Melting point | 238 °C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Slightly) | | color | White to Off-White | | Merck | 14,680 | | CAS DataBase Reference | 2508-72-7(CAS DataBase Reference) |
| | Antazoline Hcl Usage And Synthesis |
| Chemical Properties | White or almost white crystalline powder | | Originator | Antistine HCl,Ciba,US,1948 | | Uses | Imidazoline binding site ligand and an antihistamine | | Uses | Antihistaminic;H1 antagonist | | Uses | Antazoline Hydrochloride acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical. | | Manufacturing Process | 15.4 parts of 2-chloromethylimidazoline hydrochloride, 45.8 parts of Nbenzylaniline
and 150 parts of alcohol are heated in an oil bath at 100° to
110°C. After distilling off the alcohol, the reaction mass is maintained at this
temperature for a further 3 hours and then triturated with water and 10 parts
of sodium bicarbonate. The unconsumed benzylaniline is extracted with ether
and the aqueous solution neutralized with dilute hydrochloric acid. By
evaporating this solution and extracting the residue with alcohol there is
obtained 2-(N-phenyl-N-benzylaminomethyl)imidazoline hydrochloride in the form of colorless crystals of melting point 227° to 229°C. | | Therapeutic Function | Antihistaminic | | Biological Activity | Imidazoline binding site ligand; a potent inducer of insulin secretion in rat pancreas. Also an antihistamine. |
| | Antazoline Hcl Preparation Products And Raw materials |
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