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Isoprenaline

Isoprenaline Suppliers list
Company Name: Ligard Anesthesia  
Tel: 09062331627
Email:
Products Intro: Cas:7683-59-2
ProductName:isoprenaline
Company Name: Pharmaffiliates Analytics and Synthetics P. Ltd  
Tel: +91-172-5066494
Email: mktg@pharmaffiliates.com
Products Intro: Cas:7683-59-2
ProductName:Isoprenaline
Brand:pharmaffiliates | Product Number:PA0981000
Company Name:   
Tel:
Email: sales@clearsynth.com
Products Intro: Cas:7683-59-2
ProductName:Isoprenaline
Brand:clearsynth | Product Number:CS-ED-00292
Company Name: AK Scientific, Inc.  
Tel: 650 494 8666
Email: sales@aksci.com
Products Intro: Cas:7683-59-2
ProductName:Isoprenaline
Brand:aksci | Product Number:0117BA
Company Name: Changzhou Xianglong Pharmaceutical Technology Co., LTD  
Tel: 0519-88910898 18661161657
Email: yaoxiangqiu2021@163.com
Products Intro: Cas:7683-59-2
ProductName:Isoprenaline hydrochloride EP Impurity A
Purity: 95% | Package: 10mg;25mg;50mg;100mg

Isoprenaline manufacturers

Isoprenaline Basic information
Product Name:Isoprenaline
Synonyms:4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;isoproterenol;4-(1-hydroxy-2-(isopropylaMino)ethyl)benzene-1,2-diol;isoprel;saventrine;Isoproterenol (base and/or unspecified salts);4-(2-Isopropylamino-1-hydroxyethyl)-1,2-benzenediol;4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol
CAS:7683-59-2
MF:C11H17NO3
MW:211.26
EINECS:231-687-7
Product Categories:
Mol File:7683-59-2.mol
Isoprenaline Structure
Isoprenaline Chemical Properties
Melting point 170.5°C
Boiling point 350.94°C (rough estimate)
density 1.1240 (rough estimate)
refractive index 1.5718 (estimate)
pka8.64(at 25℃)
NIST Chemistry Reference3,4-Dihydroxy-«alpha»-(isopropylaminomethyl)-benzyl alcohol(7683-59-2)
Safety Information
MSDS Information
Isoprenaline Usage And Synthesis
UsesIsoprenaline is a non-selective β-adrenergic receptor agonist.It is used to treat heart block and episodes of Adams–Stokes syndrome that are not caused by ventricular tachycardia or fibrillation. It is also used to prevent Torsades de Pointes in patients with long QT refractory to magnesium and to treat patients with intermittent Torsades de Pointes refractory to treatment with magnesium.
Brand name

Isoprenaline is marketed under many brand names worldwide, including Aleudrina, Asthpul, Iludrin, Isomenyl, Isuprel, Neo-Epinine, Neodrenal, Proternol, and Saventrine.

Mechanism of actionIsoprenaline is a β1 and β2 adrenoreceptor agonist and has almost no activity on alpha adrenergic receptors at low levels.However, at higher concentrations, isoprenaline can evoke α-AR-mediated responses. Its agonist effects at TAAR1 provide it with pharmacodynamic effects that resemble those of the endogenous trace amines, like tyramine.
Pharmacology

Isoprenaline has a positive inotropic and chronotropic effects, increasing cardiac output by increasing the heart rate and cardiac contractility. Isoprenaline also decreases diastolic blood pressure by lowering peripheral vascular resistance.

Side effects

Tachycardia, cardiac arrhythmias, palpitations, hypotension, hypertension

Tremor

Headache, dizziness

Sweating, facial flushing

Both isoprenaline salts have a low pH and may cause venous irritation and tissue damage in cases of extravasation.

Isoprenaline Preparation Products And Raw materials
Raw materialsCatechol-->3,4-dihydroxy--chloroacetophenone-->Sulfuric acid-->Hydrogen-->Isopropylamine
Preparation Products1H-Indole-5,6-dione, 2,3-dihydro-3-hydroxy-1-(1-methylethyl)-
Tag:Isoprenaline(7683-59-2) Related Product Information
Norepinephrine 4-tert-Butylcatechol Hydroquinone 1-Hydroxyethylidene-1,1-diphosphonic acid Ethylbenzene Resorcinol L(-)-Epinephrine Ethyl acetate Catechol Ethylparaben tert-Butylhydroquinone Allylbenzene Ethyl acrylate Benzene CHLOROPHOSPHONAZO III Epinephrine Hydrochloride Clorprenaline (PLUS-MINUS)-ISOPROTERENOL*HYDROCHLORIDE,ISOPROTERENOL HYDROCHLORIDE,(+/-)-ISOPROTERENOL HYDROCHLORIDE,DL-ISOPROTERENOL HYDROCHLORIDE,Isoproterenol, HCl