| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
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info@lynnchem.com |
| Products Intro: |
Product Name:COCHLIOQUINONE A
CAS:32450-25-2
Purity:>99% by HPLC Package:1mg;5mg
|
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Email: |
info@novachemistry.com |
| Products Intro: |
Product Name:Cochlioquinone A
CAS:32450-25-2
Purity:>99% by HPLC Package:1mg;5mg
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Cochlioquinone A
CAS:32450-25-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
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| | COCHLIOQUINONE A Basic information |
| Product Name: | COCHLIOQUINONE A | | Synonyms: | COCHLIOQUINONE A;(3R)-9-[(1S,2R,3S)-2-Acetyloxy-1,3-dimethylpentyl]-1,2,3,4aβ,5,6,6a,12,12aβ,12b-decahydro-12β-hydroxy-3α-(1-hydroxy-1-methylethyl)-6aα,12bα-dimethylpyrano[3,2-a]xanthene-8,11-dione;Luteoleersin;Cochlioquinone;Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12S,12aS,12bR)-;Coclioquinone A;(2S,3R,4S)-2-[(3R,4aR,6aR,12S,12bR)-12-hydroxy-3-(2-hydroxypropan-2-yl)-6a,12b-dimethyl-8,11-dioxo-1,2,3,4a,5,6,12,12a-octahydropyrano[3,2-a]xanthen-9-yl]-4-methylhexan-3-yl] acetate | | CAS: | 32450-25-2 | | MF: | C30H44O8 | | MW: | 532.67 | | EINECS: | | | Product Categories: | Antibiotic | | Mol File: | 32450-25-2.mol |  |
| | COCHLIOQUINONE A Chemical Properties |
| Melting point | 135 °C | | Boiling point | 638.8±55.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble | | form | A yellow lyophilisate | | pka | 11.57±0.70(Predicted) |
| | COCHLIOQUINONE A Usage And Synthesis |
| Uses | Cochlioquinone A is an antagonist of CCR5. Diacylglycerol kinase inhibitor. | | Uses | Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 μM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 μM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 μM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 μM.[Cayman Chemical] | | Uses | Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A has recently been shown to be an antagonist of the human chemokine receptor, CCR5, in HIV-1,). Cochlioquinone A is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase. | | Definition | ChEBI: Cochlioquinone A is a member of oxanes. |
| | COCHLIOQUINONE A Preparation Products And Raw materials |
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