- L-xylose
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- $0.00 / 1KG
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2023-01-06
- CAS:609-06-3
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 500kg/month
- L-XYLOSE
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- $0.00 / 1kg
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2022-12-07
- CAS:609-06-3
- Min. Order: 1kg
- Purity: 98.0%min
- Supply Ability: 10tons/year
- L-XYLOSE
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- $15.00 / 1KG
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2021-08-12
- CAS:609-06-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | L-xylose Basic information |
| | L-xylose Chemical Properties |
| Melting point | 150-152 °C(lit.) | | Boiling point | 191.65°C (rough estimate) | | density | 1.525 | | refractive index | -20 ° (C=10, H2O) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | H2O: 0.1 g/mL, clear, colorless | | pka | 12.46±0.20(Predicted) | | form | Crystalline Powder | | color | White to off-white | | optical activity | [α]24/D 18.7°, c = 4 in H2O | | Water Solubility | within almost transparency | | Sensitive | Hygroscopic | | BRN | 1723080 | | InChIKey | SRBFZHDQGSBBOR-VVZXFQNISA-N | | LogP | -2.390 (est) | | CAS DataBase Reference | 609-06-3(CAS DataBase Reference) | | EPA Substance Registry System | L-Xylose (609-06-3) |
| | L-xylose Usage And Synthesis |
| Chemical Properties | L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.
Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form. | | Uses | L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes. | | Definition | ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration. | | Application | l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007). | | Preparation | L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985). |
| | L-xylose Preparation Products And Raw materials |
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