| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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| Tel: |
18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE
CAS:484-49-1
Purity:98% Package:1g，10g，100g，1kg
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| | 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Basic information |
| | 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Chemical Properties |
| | 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Usage And Synthesis |
| Description | This alkaloid has recently been shown to exhibit a marked antineoplastic activity.
Administration of 25 or 50 mg/kg intraperitoneally on alternate days or daily until
death to mice which had been inoculated with a single intraperitoneal dose of
106 -102 LI2l0 leukemia cells increased the survival time by 89-229 per cent
compared with control animals.
Japanese workers have recently reported the synthesis of olivacine by heating
indole with 4(1-hydroxyethyl)-3-methoxymethyl-2-methylpyridine in 47 per
cent HBr. | | Definition | ChEBI: Olivacine is a member of carbazoles. | | Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 27, p. 1751, 1990 DOI: 10.1002/jhet.5570270645 | | References | Regina et al., Cienc. Cult. (Sao Paulo), 26, 517 (1974)
Synthesis:
Kametani et al., J. Chern. Soc., Perkin I, 2102 (1975) |
| | 1,5-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE Preparation Products And Raw materials |
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