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Company Name: Capot Chemical Co.,Ltd.
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Email: sales@capotchem.com
Products Intro: Product Name:7-Nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile
CAS:115066-14-3
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
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Email: sale04@alfachem.cn
Products Intro: CAS:115066-14-3
Purity:98% Package:5g; 25g; 100g; 500g; 1kg; 25kg
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
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Products Intro: Product Name:CNQX
CAS:115066-14-3
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: AFINE CHEMICALS LIMITED
Tel: 0571-85134551 18958018566;
Email: info@afinechem.com
Products Intro: Product Name:6-CYANO-7-NITROQUINOXALINE-2,3-DIONE
CAS:115066-14-3
Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
Company Name: Zhejiang J&C Biological Technology Co.,Limited
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Products Intro: Product Name:CNQX
CAS:115066-14-3
Purity:99% Package:5KG;1KG Remarks:CNQX

CNQX manufacturers
CNQX Basic information
Product Name:CNQX
Synonyms:7-Nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile;6-CYANO-7-NITROQUINOXALINE-2,3 (1H,4H)-DIONE;CNQX;CNQX 2NA;CNQX DISODIUM;CNQX DISODIUM SALT;FG-9065;CNQX DISODIUM KAINATE/AMPA RECEPTOR
CAS:115066-14-3
MF:C9H4N4O4
MW:232.15
EINECS:
Product Categories:Heterocyclic Compounds;Neurochemicals;Glutamate receptor;Glutamate;Aromatics;Heterocycles
Mol File:115066-14-3.mol
CNQX Structure
CNQX Chemical Properties
Melting point 300 °C
Boiling point 374.31°C (rough estimate)
density 1.5507 (rough estimate)
refractive index 1.6590 (estimate)
RTECS VD1520000
storage temp. protect from light
solubility H2O: 10 mg/mL
form solid
pka8.16±0.20(Predicted)
color orange to red
Stability:Store Tightly Sealed at RT
CAS DataBase Reference115066-14-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 22-24/25
WGK Germany 3
HS Code 29335990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
CNQX Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesCNQX disodium salt hydrate has been used as:
  • as a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures(110)
  • as a glutamatergic blockers for measuring inhibitory postsynaptic currents in projection neurons(111)
  • as a AMPA glutamate receptor antagonist prefrontal cortex neurons(112)

UsesA potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively
UsesCNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors). This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.
DefinitionChEBI: 6-Cyano-7-nitroquinoxaline-2,3-dione is a quinoxaline derivative.
Biological ActivityPotent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex.
Biochem/physiol ActionsPotent, competitive AMPA/kainate glutamate receptor antagonist.
storageRoom temperature
CNQX Preparation Products And Raw materials
Tag:CNQX(115066-14-3) Related Product Information
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