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(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE

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(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Dihydro-β-erythroidine hydrobromide；DHβE hydrobromide
CAS:29734-68-7
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hefei Hirisun Pharmatech Co., Ltd
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Products Intro: Product Name:(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
CAS:29734-68-7
Purity:0.95 Package:1G;5G;25G;Bulk for inquiry Remarks:HR130795
Company Name: Shanghai Acmec Biochemical Technology Co., Ltd.
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Products Intro: Product Name:Dihydro-β-erythroidine hydrobromide
CAS:29734-68-7
Purity:98% Package:5mg, 10mg
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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Products Intro: Product Name:Dihydro-β-erythroidine hydrobroMide;(2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-onehydrobroMide
CAS:29734-68-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: EMMX Biotechnology LLC  
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Products Intro: Product Name:Dihydro-β-erythroidine hydrobromide
CAS:29734-68-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Basic information
Product Name:(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE
Synonyms:(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE;3BETA-1,6-DIDEHYDRO-14,17-DIHYDRO-3-METHOXY-16(15H)-OXAERYTHRINAN-15-ONE HYDROBROMIDE;DIHYDRO-B-ERYTHROIDINE HYDROBROMIDE;DIHYDRO-BETA-ERYTHROIDINE HYDROBROMIDE;DIHYDRO-B-ERYTHROIDINE HYDROBROMIDE COMP ETITIVE NICOTINIC;3β-1,6-Didehydro-14,17-dihydro-3-methoxy-16(15H)-oxaerythrinan-15-one hydrobromide;Dihydro-β-erythroidine hydrobromide;-erythroidine hydrobromide
CAS:29734-68-7
MF:C16H21NO3.BrH
MW:356.25
EINECS:
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Mol File:29734-68-7.mol
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Structure
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Chemical Properties
storage temp. Desiccate at RT
solubility ethanol: 5mg/mL
form solid
Melting point 219-229 °C (decomp)
color white
Safety Information
Safety Statements 22-36
WGK Germany 3
RTECS KF3325000
MSDS Information
ProviderLanguage
SigmaAldrich English
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Usage And Synthesis
UsesDihydro-β-erythroidine is an alkaloid isolated from the seeds of erythrina and a competitive antagonist at the nicotinic acetylcholine receptor (nAChR).
DefinitionChEBI: Dihydro-beta-erythroidine hydrobromide is a member of indoles.
Biological ActivityCompetitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α 4 receptor subunit (IC 50 values are 0.19 and 0.37 μ M for α 4 β 4 and α 4 β 2 receptors respectively). Antagonizes behavioral effects of nicotine in vivo .
in vitrodhβe has been shown to be a purely competitive antagonist of the neuronal nicotinic receptor [1].
in vivodhβe is able to block some of the central actions of nicotine after systemic and intrathecal administration. the mechanism of blockade is different from that of mecamylamine, a classical ganglionic antagonist, and may involve a direct action of dhβe on nicotine receptor [2].
IC 501.3 μm for α2β2, 2.3 μm for α2β4, 0.41 μm for α3β2, 23.1 μm for α3β4, 0.37 μm for α4β2, and 0.19 μm for α4β4 [1]
storageDesiccate at RT
references[1] harvey sc, maddox fn, luetje cw. multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits. j neurochem. 1996 nov;67(5):1953-9.
[2] damaj mi, welch sp, martin br. in vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice. psychopharmacology (berl). 1995 jan;117(1):67-73.
[3] murphree hb. effects in human volunteers of subparalytic doses of dihydro-beta-erythroidine. clin pharmacol ther. 1963 may-jun;4:304-10.
(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE Preparation Products And Raw materials
Tag:(2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE(29734-68-7) Related Product Information
Methyl hex-3-enoate trans-3-Hexenoic acid VIGABATRIN 2-(1-CYCLOHEXENYL)ETHYLAMINE [2-(cyclohex-1-en-1-yl)ethyl](ethyl)amine 4-(2-CYCLOHEX-1-ENYL-ETHYLAMINO)-BUTAN-1-OL (S)-CYCLOHEX-2-ENYLAMINE, 95%, (98% E.E.) 3-Pyrrolidin-2-yl-propionic acid 3-Pyrrolidin-2-yl-propan-1-ol ETHYL 5-METHYL-5-HEXENOATE 7-AMINO-HEPTANOIC ACID HCL ,98.0+% Ethyl 8-nonenoate (2S,13BS)-2-METHOXY-2,3,5,6,8,9,10,13-OCTAHYDRO-1H,12H-BENZO[I]PYRANO[3,4-G]INDOLIZIN-12-ONE HYDROBROMIDE [2-(cyclohex-1-en-1-yl)ethyl](propyl)amine Diprobutine 1-(3-BUTENYL)PYRROLIDINE (E)-NONA-2,8-DIEN-1-OL