- 3-Aminopyrazole
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- $10.00 / 1kg
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2024-04-25
- CAS:1820-80-0
- Min. Order: 1kg
- Purity: 99.6%
- Supply Ability: 100000
- 3-Aminopyrazole
-
- $1.00 / 1KG
-
2024-04-20
- CAS:1820-80-0
- Min. Order: 1KG
- Purity: 99.91%
- Supply Ability: 200000
- 3-Aminopyrazole
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- $0.00 / 200KG
-
2023-09-06
- CAS:1820-80-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500000kg
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| | 3-Aminopyrazole Basic information |
| | 3-Aminopyrazole Chemical Properties |
| Melting point | 34-37 °C (lit.) | | Boiling point | 218 °C/122 mmHg (lit.) | | density | 1.0248 (rough estimate) | | refractive index | 1.5060 (estimate) | | Fp | >230 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | soluble in Methanol | | pka | 15.28±0.10(Predicted) | | form | Oily Liquid or Crystalline Low Melting Solid | | color | White to light yellow | | Sensitive | Air & Light Sensitive | | BRN | 1618 | | InChIKey | JVVRJMXHNUAPHW-UHFFFAOYSA-N | | CAS DataBase Reference | 1820-80-0(CAS DataBase Reference) | | NIST Chemistry Reference | 3(5)-aminopyrazole(1820-80-0) |
| | 3-Aminopyrazole Usage And Synthesis |
| Chemical Properties | 3-Aminopyrazole is Low-Melting Yellow Solid | | Uses | 3-Aminopyrazole is used in the preparation of heterocyclic compounds of pharamaceutical interest | | Uses | Employed in a one-pot synthesis of pyrazolopyrimidines.1 | | Uses | 3-Aminopyrazole was used in the spectroscopic characterization of ferrocenoyl peptides via 1H-NMR spectroscopy. It was also used in the synthesis of:
- symmetrical dialkylpyrazolo[1,5-a]pyrimidines via condensation with symmetrical β-diketones
- 3,4-annelated coumarins
- heterocyclic compounds of pharmaceutical interest
- pyrazolopyrimidines
| | General Description | 3-Aminopyrazole is a heteroarylamine. | | Synthesis | The synthesis of 3-Aminopyrazole is as follows:A solution of 50 mg (0.34 mmol) of 3-oxo-3-phenylpropanenitrile and 11.6 mg (0.36 mmol) of hydrazine and 0.024 mL of acetic acid (0.37 mmol) in 3 mL of anhydrous ethanol was heated at 60° C for 24 hr. The mixture was cooled to ambient temperature and the solvent removed in vacuo. The residue was taken up in ethyl acetate, washed with saturated sodium bicarbonate. The organic layer was washed with brine and dried over MgSO4, filtered and evaporated. The solid residue waswashedwithethyl ether and dried in vacuo to give 45 mg (82%) of 3-phenyl-1H-pyrazol-5-amine.
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| | 3-Aminopyrazole Preparation Products And Raw materials |
| Preparation Products | 4-CHLORO-2-METHYLTHIOPYRAZOLO[1,5-A]1,3,5-TRIAZINE-->1H-Pyrazolo[3,4-b]pyridin-3-amine-->1H-PYRAZOLO[3,4-B]PYRIDINE, 3-BROMO--->3-NITRO-1H-PYRAZOLO[3,4-B]PYRIDINE-->8-BROMO-4-CHLORO-2-METHYLTHIOPYRAZOLO[1,5-A]1,3,5-TRIAZINE-->1H-PYRAZOLO[3,4-B]PYRIDINE-->5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE-->3-Acetylaminopyrazole-->3-Amino-4-bromopyrazole-->5-Nitro-1H-pyrazolo[3,4-b]pyridine-->3-AMino-4-iodo-1H-pyrazole, 97%-->1174229-22-1-->1-(4-FLUORO-BENZYL)-1H-PYRAZOL-3-YLAMINE-->1-{[4-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-amine-->7-Methylpyrazolo[1,5-a]pyriMidin-5(4H)-one |
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