- Mitiglinide calcium
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- $0.00 / 1kg
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2023-11-01
- CAS:207844-01-7
- Min. Order: 1kg
- Purity: 99.0% min
- Supply Ability: 1000kgs/month
- Mitiglinide calcium
-
- $1.00 / 1kg
-
2023-08-16
- CAS:207844-01-7
- Min. Order: 1kg
- Purity: >99%
- Supply Ability: 6000ton
- Mitiglinide Calcium
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- $200.00 / 1kg
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2023-06-26
- CAS:207844-01-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg/Month
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| | Mitiglinide calcium dihydrate Basic information |
| Product Name: | Mitiglinide calcium dihydrate | | Synonyms: | (aS,3aR,7aS)-Octahydro-gamma-oxo-alpha-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt dihydrate;(S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid calcium salt dihydrate;3006 MITIGLINIDE CALCIUM HYDRATE;2H-ISOINDOLE-2-BUTANOICACID,OCTAHYDRO-G-OXO-A-(PHENYLMETHYL)-,CALCIUMSALT,DIHYDRATE;Mitiglinide CalciuM dihydrate;(S)-2-Benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric Acid Calcium Salt Hydrate;Mitiglinide calciuM salt dihydrate;2H-Isoindole-2-butanoicacid, octahydro-g-oxo-a-(phenylMethyl)-, calciuM salt,hydrate (2:1:2), (aS,3aR,7aS)- | | CAS: | 207844-01-7 | | MF: | C38H52CaN2O8 | | MW: | 704.91 | | EINECS: | 1308068-626-2 | | Product Categories: | APIs;Antidiabetic;API;Diabetes Research;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents | | Mol File: | 207844-01-7.mol |  |
| | Mitiglinide calcium dihydrate Chemical Properties |
| Melting point | 179-185°C | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Methanol (Slightly) | | form | Solid | | color | White | | InChIKey | QEVLNUAVAONTEW-HNIWBTCONA-L | | SMILES | N1(C[C@]2([H])CCCC[C@]2([H])C1)C(=O)C[C@H](CC1=CC=CC=C1)C(=O)O[Ca]OC(=O)[C@@H](CC1=CC=CC=C1)CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1.O.O |&1:2,8,14,29,42,48,r| | | CAS DataBase Reference | 207844-01-7(CAS DataBase Reference) |
| | Mitiglinide calcium dihydrate Usage And Synthesis |
| Description | Mitiglinide calcium hydrate (KAD-1229) is an insulinotropic agent. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels. | | Chemical Properties | White Solid | | Uses | KAD-1229 Calcium Hydrate (Mitiglinide calcium dihydrate) could binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic.
| | Mechanism of action | Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels in pancreatic beta-cells, and its early insulin release and short duration of action would be effective in improving postprandial hyperglycemia. |
| | Mitiglinide calcium dihydrate Preparation Products And Raw materials |
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