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| (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Basic information |
Product Name: | (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE | Synonyms: | (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE;PD 81,723;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone;(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone | CAS: | 132861-87-1 | MF: | C14H12F3NOS | MW: | 299.31 | EINECS: | | Product Categories: | Adenosine receptor | Mol File: | 132861-87-1.mol | |
| (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Chemical Properties |
Melting point | 100-104 °C(Solv: ligroine (8032-32-4)) | Boiling point | 411.7±45.0 °C(Predicted) | density | 1.328±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,2-8°C | solubility | DMSO: ~13 mg/mL | form | solid | pka | -1.36±0.13(Predicted) | color | yellow |
| (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Usage And Synthesis |
Uses | PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs. | Biological Activity | Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo . | storage | Store at RT |
| (2-AMINO-4,5-DIMETHYL-3-THIENYL)-[3-(TRIFLUOROMETHYL)PHENYL]METHANONE Preparation Products And Raw materials |
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