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| | METHOXYRESORUFIN Basic information |
| Product Name: | METHOXYRESORUFIN | | Synonyms: | 7-methoxyresorufin;O7-METHYLRESORUFINE;RESORUFIN 7-O-METHYL ETHER;RESORUFIN METHYL ETHER;7-METHOXY-3H-PHENOXAZIN-3-ONE;METHOXYRESORUFIN;O(7)-METHYLRESORUFINE, FOR FLUOR-ESCENCE;3H-Phenoxazin-3-one, 7-methoxy- | | CAS: | 5725-89-3 | | MF: | C13H9NO3 | | MW: | 227.22 | | EINECS: | | | Product Categories: | | | Mol File: | 5725-89-3.mol |  |
| | METHOXYRESORUFIN Chemical Properties |
| Melting point | ≥220 °C(lit.) | | Boiling point | 378.8±42.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: soluble | | pka | 1.42±0.20(Predicted) | | form | Powder | | BRN | 209529 |
| | METHOXYRESORUFIN Usage And Synthesis |
| Description | Methoxyresorufin is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. Methyoxyresorufin is O-demethylated by CYP1A1/2, releasing resorufin, which displays excitation/emission maxima of 570/580 nm, respectively. The appearance of resorufin fluorescence can be used to quantify CYP1A1/2 activity. | | Uses | Substrate for Cytochrome P-450. METHOXYRESORUFIN is used for various investigations including the differentiatiation of cytochrome P-450 isozymes. | | Uses | Used to differentiate isozymes of cytochrome P-450 | | Uses | Resorufin methyl ether have been used as substrate in the incubation mixture, during the determination of cytochrome P4501A activities such as ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase(MROD) in liver microsomes, using high performance liquid chromatography(HPLC). | | Biochem/physiol Actions | Fluorimetric substrate for cytochrome P450 linked enzymes. |
| | METHOXYRESORUFIN Preparation Products And Raw materials |
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