- Rink Amide Linker
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- $100.00 / 1kg
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2024-05-24
- CAS:145069-56-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 200Tons
- Fmoc -Rink Linker
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- $0.00 / 1kg
-
2024-05-24
- CAS:145069-56-3
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | Rink Amide Linker Basic information |
| Product Name: | Rink Amide Linker | | Synonyms: | Rink AMid Linker, (FoMc-AM, Knorr linker);Rink AMind Linker;FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE;4-[(2,4-DiMethoxyphenyl)(FMoc-aMino)Methyl]phenoxyacetic acid, 98+%;RINK AMIDE REAGENT;N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID;P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID;P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID | | CAS: | 145069-56-3 | | MF: | C32H29NO7 | | MW: | 539.58 | | EINECS: | 604-455-1 | | Product Categories: | Linkers for Solid Phase Synthesis;Linkers for solid phase synthesis;PROTECTED AMINO ACID & PEPTIDES;Pharmaceutical Raw Materials | | Mol File: | 145069-56-3.mol |  |
| | Rink Amide Linker Chemical Properties |
| Melting point | ~180 °C (dec.) | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | BRN | 5841553 | | InChIKey | UPMGJEMWPQOACJ-UHFFFAOYSA-N | | SMILES | C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1 | | CAS DataBase Reference | 145069-56-3(CAS DataBase Reference) |
| | Rink Amide Linker Usage And Synthesis |
| Uses | Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug. | | Application | Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1]. | | Origin | Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker. | | References | [1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.
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| | Rink Amide Linker Preparation Products And Raw materials |
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