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HEXAMETHONIUM CHLORIDE

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Company Name: Career Henan Chemica Co
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Products Intro: Product Name:HEXAMETHONIUM CHLORIDE
CAS:60-25-3
Purity:95.0% windy 277
Company Name: Chemsigma International Co., Ltd.
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Products Intro: Product Name:HEXAMETHONIUM CHLORIDE
CAS:60-25-3
Purity:98% Package:25KG;5KG;1KG
Company Name: Alfa Chemistry
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Products Intro: Product Name:HEXAMETHONIUM CHLORIDE
CAS:60-25-3
Company Name: Wuhan Fortuna Chemical Co., Ltd
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Products Intro: Product Name:Hexamethonium chloride
CAS:60-25-3
Purity:98%min Package:1KG
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
Tel: 571-88938639 +8617705817739
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Products Intro: Product Name:Hexamethonium Chloride Dihydrate
CAS:60-25-3
Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Hot selling

HEXAMETHONIUM CHLORIDE manufacturers

  • Hexamethonium chloride
  • Hexamethonium chloride pictures
  • $0.00 / 1KG
  • 2023-01-18
  • CAS:60-25-3
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
HEXAMETHONIUM CHLORIDE Basic information
Product Name:HEXAMETHONIUM CHLORIDE
Synonyms:6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dichloride;hexonchloride;hexonechloride;hiohexchloride;methiumchloride;A,W-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE;HEXAMETHYLENEBIS[TRIMETHYLAMMONIUM CHLORIDE];HEXAMETHONIUM CHLORIDE
CAS:60-25-3
MF:C12H30Cl2N2
MW:273.29
EINECS:200-465-1
Product Categories:Ammonium Chlorides (Quaternary);Quaternary Ammonium Compounds
Mol File:60-25-3.mol
HEXAMETHONIUM CHLORIDE Structure
HEXAMETHONIUM CHLORIDE Chemical Properties
Melting point 292°C(dec.)(lit.)
Boiling point 423.36°C (rough estimate)
density 1.0558 (rough estimate)
refractive index 1.6400 (estimate)
solubility H2O: soluble
form solid (hygroscopic)
color white
Water Solubility almost transparency
BRN 3714806
CAS DataBase Reference60-25-3
EPA Substance Registry System1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)
Safety Information
WGK Germany 3
RTECS BQ8650000
HS Code 2923.90.0100
MSDS Information
ProviderLanguage
SigmaAldrich English
HEXAMETHONIUM CHLORIDE Usage And Synthesis
Chemical PropertiesWhite, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.
UsesHexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.
UsesMedicine (antihypertensive).
UsesHexamethonium Chloride is a ganglionic nicotinic receptor blocker.
General DescriptionNicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.
Biochem/physiol ActionsHexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.
HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials
Raw materials1,6-Dichlorohexane-->Trimethylamine
Tag:HEXAMETHONIUM CHLORIDE(60-25-3) Related Product Information
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