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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

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((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Suppliers list
Company Name: NewCan Biotech Limited
Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Products Intro: Product Name:(2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-D-ribono-r-lactone
CAS:874638-80-9
Purity:97% Package:mgs,gs,kgs
Company Name: JIANGXI TIME PHARMACEUTICAL CO.,LTD
Tel: +86-0794-7183888 +86-13155888520
Email: sales@groupchem.com
Products Intro: Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl -5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS:874638-80-9
Purity:98% Package:25KG
Company Name: Henan Bao Enluo International TradeCo.，LTD
Tel: +86-17331933971 +86-17331933971
Email: deasea125996@gmail.com
Products Intro: Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS:874638-80-9
Purity:99% Package:1kg;10USD
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS:874638-80-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS:874638-80-9
Purity:99% Package:100g ;1KG ;5KG 25KG

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate manufacturers
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Basic information
Product Name:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Synonyms:3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-γ-latone;SFBM;(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid γ-lactone 3,5-dibenzoate;Sofosbuvir intermediate;Sofosbuvir Impurity 30;3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone;(2R,3R,4R)-2-[(benzoyloxy)methyl]-4-fluoro-4-methyl-5-oxooxolan-3-yl benzoate;Sofosbuvir Intermediate 1
CAS:874638-80-9
MF:C20H17FO6
MW:372.35
EINECS:618-021-4
Product Categories:apis;Sofosbuvir intermediate
Mol File:874638-80-9.mol
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Structure
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Chemical Properties
Melting point 133℃
Boiling point 458.6±34.0 °C(Predicted)
density 1.33
storage temp. 2-8°C
Safety Information
MSDS Information
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Usage And Synthesis
Uses(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
Usesneuromuscular blocking agent
Application((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.
((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Preparation Products And Raw materials
Raw materialsD-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester-->(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one-->Benzoyl chloride
Tag:((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate(874638-80-9) Related Product Information
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) Sofosbuvir Impurity 17 L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester L-Alanine isopropyl ester hydrochloride (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate PSI-6130 derivative D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester 2'-deoxy-2'-fluoro-2'-C-methyluridine Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate sofosBuvir impurity 36 SofosBuvir Impurity 55 Sofosbuvir impurity E SofosBuvir Impurity 40 SofosBuvir Impurity 54