- Tenovin-6
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- $5.00 / 5KG
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2019-09-04
- CAS:1011557-82-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1ton
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| | Tenovin-6 Basic information |
| Product Name: | Tenovin-6 | | Synonyms: | Tenovin-6;4-TERT-BUTYL-N-(4-(5-(DIMETHYLAMINO)PENTANAMIDO)PHENYLCARBAMOTHIOYL)BENZAMIDE HYDROCHLORIDE;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide;Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide Tenovin-6;Tenovin-6, >=98%;4-(tert-Butyl)-N-((4-(4-(dimethylamino)butanamido)phenyl)carbAmothioyl)benzamide;Tenovin 6 - Tnv 6 | | CAS: | 1011557-82-6 | | MF: | C25H34N4O2S | | MW: | 454.63 | | EINECS: | 200-256-5 | | Product Categories: | Inhibitors | | Mol File: | 1011557-82-6.mol |  |
| | Tenovin-6 Chemical Properties |
| density | 1.171±0.06 g/cm3(Predicted) | | storage temp. | Store at -20° C | | solubility | ≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic | | form | solid | | pka | 9.11±0.70(Predicted) |
| | Tenovin-6 Usage And Synthesis |
| Uses | Tenovin-6 Hydrochloride, is a small molecule activator of p53 transcriptional activity. It acts as a potent SIRT1 and SIRT2 inhibitor as well. | | Definition | ChEBI: Tenovin-6 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(dimethylamino)pentanoic acid with the aromatic amino group of N-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide. It has a role as an antineoplastic agent, a Sir2 inhibitor and a p53 activator. It is a monocarboxylic acid amide, a member of thioureas and a tertiary amino compound. | | target | SIRT1 |
| | Tenovin-6 Preparation Products And Raw materials |
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