(SAR9,MET(O2)11)-SUBSTANCE P manufacturers
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| | (SAR9,MET(O2)11)-SUBSTANCE P Basic information |
| Product Name: | (SAR9,MET(O2)11)-SUBSTANCE P | | Synonyms: | H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2;ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2;(SAR9,MET(O2)11)-SUBSTANCE P;RPKPQQFFSARLM(O2);[SAR9 ,MET(O2 )11 ]-SUBSTANCE P HIGHLY SPECIFIC NEUROKININ NK1 RECEPTOR 97+%;[Sar9,met(o2)11]-substancephighlyspecificneurokininnk1receptor;substance P, Sar(9)-Met(O2)(11)-;[Sar9, Met(O2)11 | | CAS: | 110880-55-2 | | MF: | C64H100N18O15S | | MW: | 1393.66 | | EINECS: | | | Product Categories: | Tachykinin receptor | | Mol File: | 110880-55-2.mol |  |
| | (SAR9,MET(O2)11)-SUBSTANCE P Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | H2O : 50 mg/mL (35.88 mM; Need ultrasonic) | | pka | 13.31±0.20(Predicted) | | form | Lyophilized solid. | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2 |
| | (SAR9,MET(O2)11)-SUBSTANCE P Usage And Synthesis |
| Uses | [Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4). | | Biochem/physiol Actions | Highly selective NK-1 receptor agonist. | | storage | Store at -20°C |
| | (SAR9,MET(O2)11)-SUBSTANCE P Preparation Products And Raw materials |
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