|
|
| | Ethyl 3-Amino-4-methylbenzoate Basic information |
| Product Name: | Ethyl 3-Amino-4-methylbenzoate | | Synonyms: | AKOS BB-3093;3-AMINO-4-METHYLBENZOIC ACID ETHYL ESTER;ethyl 3-amino-4-methylbenzoate(SALTDATA: FREE);Benzoic acid, 3-aMino-4-Methyl-, ethyl ester;3-aMino-4-Methyl-, ethyl ester;Ethyl3-Amino-4-methylbenzoate>;3-Amino-p-toluic Acid Ethyl Ester;Ethyl 3-Amino-p-toluate | | CAS: | 41191-92-8 | | MF: | C10H13NO2 | | MW: | 179.22 | | EINECS: | | | Product Categories: | | | Mol File: | 41191-92-8.mol |  |
| | Ethyl 3-Amino-4-methylbenzoate Chemical Properties |
| Melting point | 48.6-50.1℃ | | Boiling point | 105°C/0.2mmHg(lit.) | | density | 1.103±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 3.35±0.10(Predicted) | | color | White to Almost white | | InChIKey | MCNBNDUVWQEKNZ-UHFFFAOYSA-N |
| | Ethyl 3-Amino-4-methylbenzoate Usage And Synthesis |
| Synthesis | Dissolve 10 g of palladium on carbon (10%) and 140 g of ammonium formate in 400 ml of methanol, and then dissolve 136 g of ethyl 3-nitro-4-methylbenzoate (2) in 400 ml of methanol. Add the methanol solution of (2) dropwise to the reaction flask at room temperature. The reaction exotherms until the methanol boils. Continue the dropwise addition. After the dropwise addition, TLC detects the completion of the reaction and filters the palladium carbon. Concentrate the methanol, add 400ml of water, and filter to obtain 156g of white solid ethyl 3-amino-4-methylbenzoate (Ethyl 3-Amino-4-methylbenzoate) as a wet product, which can be used in the next step without drying.
|
| | Ethyl 3-Amino-4-methylbenzoate Preparation Products And Raw materials |
|