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| 4-Trifluoromethoxyphenylboronic acid Basic information |
| 4-Trifluoromethoxyphenylboronic acid Chemical Properties |
Melting point | 123-127 °C(lit.) | Boiling point | 256.6±50.0 °C(Predicted) | density | 1.41±0.1 g/cm3(Predicted) | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | solubility | soluble in Methanol | pka | 8.29±0.10(Predicted) | form | Crystalline Powder | color | White to beige | BRN | 8548201 | InChIKey | HUOFUOCSQCYFPW-UHFFFAOYSA-N | CAS DataBase Reference | 139301-27-2(CAS DataBase Reference) |
| 4-Trifluoromethoxyphenylboronic acid Usage And Synthesis |
Chemical Properties | white to beige crystalline powder | Uses | B-[4-(Trifluoromethoxy)phenyl]boronic Acid is a reagent used in the synthesis of orally bioavailable matrix metalloprotinase inhibitors. Also used in the preparation of chromen-4-one inhibitors used against DNA dependant protein kinases. | Application | 4-Trifluoromethoxyphenylboronic acid can reactant involved in the synthesis of biologically active molecules including: Lactate dehydrogenase inhibitors for use against cancer cell proliferation Nitro-phenoxybenzoic acid derivatives for PAI-1 inhibition PA-824 analogs for use as antituberculosis drugs Modulators of survival motor neuron protein Reactant involved in addition reactions and cross-coupling reactions including Suzuki-Miyaura cross-coupling |
| 4-Trifluoromethoxyphenylboronic acid Preparation Products And Raw materials |
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