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| 3-Amino-2-chloro-4-methylpyridine Basic information |
| 3-Amino-2-chloro-4-methylpyridine Chemical Properties |
Melting point | 65-70 °C | Boiling point | 283.3±35.0 °C(Predicted) | density | 1.260±0.06 g/cm3(Predicted) | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | solubility | Chloroform, Ethanol | pka | 3.22±0.10(Predicted) | form | Crystals | color | Off White | InChI | InChI=1S/C6H7ClN2/c1-4-2-3-9-6(7)5(4)8/h2-3H,8H2,1H3 | InChIKey | UOBCYTOUXLAABU-UHFFFAOYSA-N | SMILES | C1(Cl)=NC=CC(C)=C1N | CAS DataBase Reference | 133627-45-9(CAS DataBase Reference) |
| 3-Amino-2-chloro-4-methylpyridine Usage And Synthesis |
Chemical Properties | Off White Crystals | Uses | 3-Amino-2-chloro-4-methylpyridine, also known as CAPIC, is a key intermediate in the production of nevirapine, a non-nucleosidic reverse transcriptase inhibitor that has been established to be clinically useful for the treatment of infection by HIV-1. | Preparation | 3-Amino-2-chloro-4-methylpyridine can be obtained by reacting 2-chloro-4-methylnicotinamide with strong bases and halides.
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| 3-Amino-2-chloro-4-methylpyridine Preparation Products And Raw materials |
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