Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:Nafadotride;N-[(1-Butyl-2-pyrrolidinyl)Methyl]-4-cyano-1-Methoxy-2-naphthalenecarboxaMide CAS:149649-22-9 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:Nafadotride CAS:149649-22-9 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing1@energy-chemical.com |
Products Intro: |
Product Name:Nafadotride CAS:149649-22-9 Purity:NULL Package:10mg;25mg Remarks:NULL
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Company Name: |
MedBioPharmaceutical Technology Inc
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Tel: |
021-69568360 18916172912 |
Email: |
order@med-bio.cn |
Products Intro: |
Product Name:N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE CAS:149649-22-9 Purity:98% Package:10mg; 50mg Remarks:Medbio
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| N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Basic information |
| N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemical Properties |
Boiling point | 556.6±40.0 °C(Predicted) | density | 1.17±0.1 g/cm3(Predicted) | storage temp. | Desiccate at RT | pka | 12.84±0.46(Predicted) |
| N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Usage And Synthesis |
Uses | Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist. | Definition | ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer
ntial dopamine D3 receptor antagonist, centrally active upon systemic administration. | Biological Activity | Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration. |
| N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Preparation Products And Raw materials |
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