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| | N,N'-Bis(phenylmethyl)-1,2-ethanediamine Basic information |
| Product Name: | N,N'-Bis(phenylmethyl)-1,2-ethanediamine | | Synonyms: | 1,2-ETHANEDIAMINE,N,N''-BIS(PHENYLMETHYL)-;N,N'-Bis(phenylmethyl)ethane-1,2-diamine;Nsc5632;N,N'-DibenzylethylenediaMine Diacetate Salt;N,N'-Dibenzylethylenediamine;n,n’-bis(phenylmethyl)-2-ethanediamine;n,n’-dibenzyl-ethylenediamin;N,N'-Dibenzyl-1,2-ethanediamine | | CAS: | 140-28-3 | | MF: | C16H20N2 | | MW: | 240.34 | | EINECS: | 205-408-4 | | Product Categories: | Nitrogen Compounds;Organic Building Blocks;Polyamines | | Mol File: | 140-28-3.mol |  |
| | N,N'-Bis(phenylmethyl)-1,2-ethanediamine Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | RIDADR | 2927 | | WGK Germany | 3 | | RTECS | KV3325000 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29215990 | | Toxicity | LD50 orl-mus: 388 mg/kg CNCRA6 52,579,68 |
| | N,N'-Bis(phenylmethyl)-1,2-ethanediamine Usage And Synthesis |
| Chemical Properties | light yellow liquid | | Uses | N,N'-Dibenzylethylenediamine is an intermediate of cephalosporin and penicillin. | | Definition | ChEBI: Benzathine is a diamine. It is a conjugate base of a benzathine(1+). | | Synthesis Reference(s) | The Journal of Organic Chemistry, 55, p. 3209, 1990 DOI: 10.1021/jo00297a042 | | Safety Profile | Poison by ingestion,intraperitoneal, and parenteral routes. When heated todecomposition it emits toxic vapors of NOx. | | Purification Methods | Dissolve DBED in acid, extract with toluene, basify, extract it with Et2O, dry over solid KOH, evaporate and fractionate it in vacuo. The diacetate crystallises from H2O by addition of EtOH and has m 111o (solubility in H2O is ~25%). The dihydrochloride has m 306-308o (from H2O) and the dipicrate has m 212o(dec) (from H2O). [Frost et al., J Am Chem Soc 71 3842 1949, Beilstein 12 H 1067, 12 III 2304.] |
| | N,N'-Bis(phenylmethyl)-1,2-ethanediamine Preparation Products And Raw materials |
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