|
|
| | (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Basic information |
| | (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Chemical Properties |
| Melting point | 185-188 °C(lit.) | | Boiling point | 472.6±28.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Soluble in Chloroform, Methanol. | | form | Fine Crystalline Powder | | color | Pink to brown | | Sensitive | Air Sensitive | | BRN | 523797 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | CQCAYWAIRTVXIY-UHFFFAOYSA-N | | CAS DataBase Reference | 2136-75-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant/Keep Cold/Air Sensitive | | HS Code | 29319090 |
| | (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Usage And Synthesis |
| Chemical Properties | pink to brown crystalline powder | | Uses | Wittig reagent for the conversion of aldehydes and ketones to two-carbon homologated, α,β-unsaturated carbonyl compounds. | | Uses | (Formylmethylene)triphenylphosphorane is used as Wittig reagent. It is also used as Pharmaceutical Intermediates. It is employed as raw material in organic Synthesis, Agrochemicals. | | Purification Methods | Recrystallise it from Me2CO, or dissolve it in *C6H6, wash with N NaOH, dry (MgSO4), evaporate, and crystallise the residue from Me2CO. It can be prepared from its precursor, formylmethyltriphenylphosphonium chloride (which crystallises from CHCl3/EtOAc), by treatment with Et3N and extraction with *C6H6. [Tripett & Walker J Chem Soc 1266 1961.] |
| | (FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE Preparation Products And Raw materials |
| Preparation Products | (3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one-->Diphenylacetylene-->VINYLCYCLOHEXANE-->3,5-BIS(BENZYLOXY)BENZYL BROMIDE-->3-NAPHTHALEN-2-YL-PROPIONALDEHYDE-->Cefdinir-->3-（trifluoromethyl) Cinnamaldehyde-->5-Nitrofuran-2-acrylaldehyde-->FENPICLONIL-->2-Propenal, 3-(2-thiazolyl)-, (2E)--->2-Propenal, 3-(3,5-difluorophenyl)-, (2E)--->(2E,2'E)-3,3'-(1,4-phenylene)diacrylaldehyde |
|