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N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE

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N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:SB228357
CAS:181629-93-6
Package:10 mg；2 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:SB228357
CAS:181629-93-6
Purity:0.98 Package:5mg，10mg，100mg，500mg，1g，5g，10g
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:SB228357
CAS:181629-93-6
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:SB 228357
CAS:181629-93-6
Purity:95% Package:$94.9/5mg;$145.9/10mg;$327.9/25mg;$610.9/50mg;$1099.9/100mg;Bulk package Remarks:95%
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Email: sales@amadischem.com
Products Intro: Product Name:N-[3-fluoro-5-(3-pyridinyl)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
CAS:181629-93-6
Purity:0.97 Package:mgs,gs,kgs Remarks:A812626
N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Basic information
Product Name:N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
Synonyms:N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE;SB 228357;N-[3-Fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide;N-[3-fluoro-5-(3-pyridinyl)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide;1H-Indole-1-carboxamide, N-[3-fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-;SB-228357,SB228357
CAS:181629-93-6
MF:C22H17F4N3O2
MW:431.38
EINECS:
Product Categories:
Mol File:181629-93-6.mol
N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Structure
N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Chemical Properties
Boiling point 625.4±55.0 °C(Predicted)
density 1.398±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ~8 mg/mL, soluble
form solid
pka9.72±0.70(Predicted)
color white
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Usage And Synthesis
UsesSB 228357 is a SR-2C/SR-2B receptor antagonist. It is used in the treatment of irritable bowel syndrome (IBS).
DefinitionChEBI: SB 228357 is an indolyl carboxylic acid.
Biological Activity5-HT 2C/2B receptor antagonist (pK i values are 7.0, 8.1 and 9.1 at 5-HT 2A , 2B and 2C receptors respectively). Displays inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT 2C receptor function. Orally active in vivo .
storageStore at RT
N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Preparation Products And Raw materials
Tag:N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE(181629-93-6) Related Product Information
6-METHYL-2,3-DIHYDRO-1H-INDOLE 3-Fluoro-5-methylaniline N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE 5-AMINO-2-METHOXYBENZOTRIFLUORIDE 3-Pyridin-3-ylaniline alpha,alpha,alpha-Trifluoro-o-cresol 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 4-Amino-2,5-dimethylphenol 4-AMINO-2-(TRIFLUOROMETHYL)PHENOL 6-(Trifluoromethyl)indoline 2-(TRIFLUOROMETHYL)ANISOLE