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| | UNOPROSTONE Basic information |
| Product Name: | UNOPROSTONE | | Synonyms: | UNOPROSTONE;9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID;Unii-6X4F561V3w;Unoprostone [inn];13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-;Alprostadil Impurity 20 | | CAS: | 120373-36-6 | | MF: | C22H38O5 | | MW: | 382.53 | | EINECS: | | | Product Categories: | | | Mol File: | 120373-36-6.mol |  |
| | UNOPROSTONE Chemical Properties |
| Boiling point | 562.9±40.0 °C(Predicted) | | density | 1.069±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml | | pka | 4.76±0.10(Predicted) |
| | UNOPROSTONE Usage And Synthesis |
| Uses | Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent. | | Definition | ChEBI: Unoprostone is an oxo monocarboxylic acid, a prostaglandins Falpha and a ketone. It has a role as an antiglaucoma drug and an antihypertensive agent. | | General Description | Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF2α analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously. |
| | UNOPROSTONE Preparation Products And Raw materials |
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