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| Melting point | 299°C dec. | | storage temp. | Inert atmosphere,2-8°C | | solubility | Soluble in water, dimethyl sulfoxide | | form | powder | | color | White | | λmax | 344 nm | | Biological Applications | Chloride indicator; nitrite indicator; diagnosis of diseases caused by elemental imbalances; detecting cancer cells,spores,stress biomarkers; identifying genes; studying chloride–bicarbonate exchange |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| Description | SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm. | | Chemical Properties | Off-White to Tan Cyrstalline Solid |
| | SPQ Preparation Products And Raw materials |
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