N-Succinimidyl-N-methylcarbamate manufacturers
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| | N-Succinimidyl-N-methylcarbamate Basic information |
| | N-Succinimidyl-N-methylcarbamate Chemical Properties |
| Melting point | 148-153 °C | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Dichloromethane (Slightly), DMSO (Slightly) | | pka | 11.00±0.46(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | Slightly soluble in water. | | Sensitive | Moisture Sensitive | | BRN | 1531863 | | CAS DataBase Reference | 18342-66-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 10-21 | | HS Code | 2928.00.5000 |
| | N-Succinimidyl-N-methylcarbamate Usage And Synthesis |
| Uses | N-Succinimidyl N-Methylcarbamate is used as a reagent in the synthesis of Argifin, a natural product chitinase inhibitor with chemotherapeutic potential. N-Succinimidyl N-Methylcarbamate is also used as a reagent in the preparation of 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide (A616300); a metabolite of Temozolomide (T017775) which is an imidazotetrazine alkylating agent and antineoplastic. | | Definition | ChEBI: N-succinimidyl N-methylcarbamate is a member of the class of pyrrolidinones that is N-hydroxysuccinimide in which the hydroxyl hydrogen is replaced by a methylcarbamoyl group. It has a role as an apoptosis inducer. It is a carbamate ester, a dicarboximide, a pyrrolidinone and a N-hydroxysuccinimide ester. It is functionally related to a succinimide. |
| | N-Succinimidyl-N-methylcarbamate Preparation Products And Raw materials |
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