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| 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Basic information |
| 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Chemical Properties |
Boiling point | 312.3±52.0 °C(Predicted) | density | 2.92±0.1 g/cm3(Predicted) | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | form | powder to crystal | pka | 10.50±0.20(Predicted) | color | White to Light yellow to Light orange | Sensitive | Light Sensitive | λmax | 282nm(lit.) | InChI | InChI=1S/C5H4IN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11) | InChIKey | HQAIUXZORKJOJY-UHFFFAOYSA-N | SMILES | C1=NC(N)=C2C(I)=NNC2=N1 |
| 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Usage And Synthesis |
Uses | 3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. |
| 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine Preparation Products And Raw materials |
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