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11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA

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Company Name: Shanghai EFE Biological Technology Co., Ltd.  
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Products Intro: Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
Purity:95% Package:50μg;100μg;500μg
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CAS:107615-77-0
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Products Intro: Product Name:11beta-13,14-dihydro-15-keto Prostaglandin F2alpha
CAS:107615-77-0
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Products Intro: Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
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Products Intro: Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
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11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Basic information
Product Name:11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA
Synonyms:9ALPHA, 11BETA-DIHYDROXY-15-OXO-PROST-5Z-EN-1-OIC ACID;11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA;11β-13,14-dihydro-15-keto Prostaglandin F2α;VKTIONYPMSCHQI-KGILNJEGSA-N;11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
MF:C20H34O5
MW:354.48
EINECS:
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Mol File:107615-77-0.mol
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Structure
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Chemical Properties
solubility 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
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MSDS Information
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Usage And Synthesis
Description11β-13,14-dihydro-15-keto PGF2α is a metabolite of PGD2 in the 15-hydroxy PGDH pathway.1,2 Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.1 Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but not 11β-13,14-dihydro-15-keto PGF2α.2 Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.2
DefinitionChEBI: 11beta-13,14-dihydro-15-keto-PGF2alpha is a prostanoid.
References1. Robinson, C., Hardy, C.C., and Holgate, S.T. The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men Biochim. Biophys. Acta 963(2),151-161(1988).
2. Robinson, C., Herbert, C.A., Bedwell, S., et al. The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways Biochem. Pharmacol. 38(19),3267-3271(1989).
11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials
Tag:11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA(107615-77-0) Related Product Information
15-KETO PROSTAGLANDIN F2ALPHA 13,14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA cis-5-Eicosenoic acid