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| | (3,4-Dimethoxyphenyl)isopropyl ketone Basic information |
| Product Name: | (3,4-Dimethoxyphenyl)isopropyl ketone | | Synonyms: | (3,4-Dimethoxyphenyl)isopropyl ketone;1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone;3',4'-Dimethoxyisobutyrophenone;1-Propanone, 1-(3,4-dimethoxyphenyl)-2-methyl-;Isobutyrophenone, 3',4'-dimethoxy-;Nsc63844;Verapamil Impurity L;Verapamil Impurity 12（Verapamil EP Impurity L） | | CAS: | 14046-55-0 | | MF: | C12H16O3 | | MW: | 208.25 | | EINECS: | | | Product Categories: | | | Mol File: | 14046-55-0.mol |  |
| | (3,4-Dimethoxyphenyl)isopropyl ketone Chemical Properties |
| Boiling point | 165-170℃ (10 Torr) | | density | 1.029±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | form | Oil | | color | Colourless |
| | (3,4-Dimethoxyphenyl)isopropyl ketone Usage And Synthesis |
| Uses | 1-(3,4-Dimethoxyphenyl)-2-methyl-1-propanone (Verapamil EP Impurity L) is a compound being considered as an inhibitor of melanogenesis. It may reduce growth or pigment production in melanocyte cells. | | Preparation | Preparation by acylation of veratrole,
with isobutyryl chloride in the presence of aluminium chloride (85%)
with isobutyric acid in the presence of PPA at 60° for 2.5 h
with isobutyric anhydride in acetonitrile in the presence of TiCl(OTf)3 /TfOH at r.t. for 12 h (89%). |
| | (3,4-Dimethoxyphenyl)isopropyl ketone Preparation Products And Raw materials |
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