| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:PNU 142633;(1S)-1-[2-[4-[4-(AMinocarbonyl)phenyl]-1-piperazinyl]ethyl]-3,4-dihydro-N-Methyl-1H-2-benzopyran-6-carboxaMide
CAS:187665-65-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:PNU 142633
CAS:187665-65-2
Purity:98% by HPLC Remarks:PNU 142633 is a selective, high affinity 5-HT1D receptor antagonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). It is an experimental drug candidate for the tre
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:PNU 142633
CAS:187665-65-2
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Basic information |
| | (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Chemical Properties |
| Boiling point | 652.5±55.0 °C(Predicted) | | density | 1?+-.0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | Soluble to 100 mM in DMSO | | form | Powder | | pka | 15.27±0.40(Predicted) |
| | (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Usage And Synthesis |
| Uses | PNU 142633 is a high affinity SR-1D agonist. | | Biological Activity | Very selective, high affinity 5-HT 1D receptor agonist (K i values are 6 and > 18000 nM at human 5-HT 1D and 5-HT 1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo . | | storage | Store at +4°C |
| | (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE Preparation Products And Raw materials |
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