- NEOMYCIN B USP/EP/BP
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- $1.10 / 1g
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2021-06-23
- CAS:119-04-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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| | NEOMYCIN B Basic information |
| Product Name: | NEOMYCIN B | | Synonyms: | (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-3-hydroxy-cyclohexoxy]tetrahydropyran-3,4-diol;neomycine standard solution;D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1?3)-O-.beta.-D-ribofuranosyl-(1?5)-O-2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1?4)-2-deoxy-;NEOMYCIN STANDARD;NEOMYCIN B;actilin;actiline;antibiotique | | CAS: | 119-04-0 | | MF: | C23H46N6O13 | | MW: | 614.64 | | EINECS: | 204-292-2 | | Product Categories: | Mechanism of Action;N;L - ZAlphabetic;NA - NIMore...Close...;AminoglycosidesAntibiotics;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics N-SAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity | | Mol File: | 119-04-0.mol |  |
| | NEOMYCIN B Chemical Properties |
| Melting point | >194°C (dec.) | | Boiling point | 658.4°C (rough estimate) | | density | 1.3548 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | 2-8°C | | solubility | Aqueous Acid (Slightly), Water (Slightly) | | form | liquid | | pka | 12.93±0.70(Predicted) | | color | clear | | Merck | 13,6482 | | Stability: | Hygroscopic |
| | NEOMYCIN B Usage And Synthesis |
| Uses | Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. | | Definition | ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. | | General Description | Chemical structure: aminoglycoside | | Biochem/physiol Actions | Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria |
| | NEOMYCIN B Preparation Products And Raw materials |
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