chloralodol

chloralodol Basic information
Product Name:chloralodol
Synonyms:chloralodol;Chlorhexadol;2-Methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)-2-pentanol;Lora;Mecoral;Medodorm;2-methyl-4-(2,2,2-trichloro-1-hydroxy-ethoxy)pentan-2-ol;2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol
CAS:3563-58-4
MF:C8H15Cl3O3
MW:265.56
EINECS:222-634-9
Product Categories:
Mol File:3563-58-4.mol
chloralodol Structure
chloralodol Chemical Properties
Melting point 102-104°
Boiling point 304.7±37.0 °C(Predicted)
density 1.348±0.06 g/cm3(Predicted)
pka10.73±0.20(Predicted)
Safety Information
DEA Controlled SubstancesCSCN: 2510
CSA SCH: Schedule III
NARC: No
MSDS Information
chloralodol Usage And Synthesis
OriginatorChloralodol,Shanghai Lancheng Corporation
UsesMechloral is a hypnotic/sedative.
DefinitionChEBI: Chloralodol is a tertiary alcohol.
Manufacturing Process472 g of 2-methyl-2,4-pentanediol (4 moles) are heated to 70°-80°C in a bowl, and 660 g of chloral hydrate (4 moles) are added under stirring until all of chloral hydrate is dissolved. The temperature, which decreases during the addition, then increased to 60° to 70°C. When reaction mixture has become a nearly dry crystal powder, the powder is subjected to further drying by slight heating. Yield of raw product is about 1060 g. Recrystallization is carried out from tetrachloromethane, and the yield is 980 g (about 92 %).
Brand nameLora (Wallace).
Therapeutic FunctionHypnotic
chloralodol Preparation Products And Raw materials
Raw materials2-Methyl-2,4-pentanediol-->2-Hydroxyethyl methacrylate-->Chloral hydrate
Tag:chloralodol(3563-58-4) Related Product Information
chloralodol Chloral hydrate 2,2,2-TRICHLORO-1-ETHOXYETHANOL