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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE

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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:FG 7142
CAS:78538-74-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:FG 7142；ZK 39106;LSU-65
CAS:78538-74-6
Purity:98.00% Package:10 mg；2 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:FG 7142
CAS:78538-74-6
Purity:98% Package:5mg Remarks:V40454
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:FG-7142
CAS:78538-74-6
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:FG 7142
CAS:78538-74-6
Purity:96% Package:$73.9/25mg;$112.9/50mg;$172.9/100mg;$389.9/250mg;Bulk package Remarks:96%
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Basic information
Description
Product Name:N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
Synonyms:4-b)indole-3-carboxamide,n-methyl-9h-pyrido(;n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide;FG 7142;N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE;B-carboline-3-carboxylic acid N-*methylamide;N-METHYL-B-CARBOLINE-3-CARBOXAMIDE (FG-7 142);beta-carboline-3-carboxylic acid N-methylamide;β-Carboline-3-carboxylic acid N-methylamide
CAS:78538-74-6
MF:C13H11N3O
MW:225.25
EINECS:
Product Categories:GABA/Glycine receptor
Mol File:78538-74-6.mol
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Structure
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Chemical Properties
Boiling point 576.3±30.0 °C(Predicted)
density 1.328±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility ethanol: 1 mg/mL
form A crystalline solid
pka13.44±0.46(Predicted)
color light tan
Safety Information
WGK Germany 3
RTECS UU9780100
MSDS Information
ProviderLanguage
SigmaAldrich English
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Usage And Synthesis
DescriptionFG 7142 (ZK 39106; LSU-65) is a nonselective benzodiazepine inverse agonist with high affinity (Ki= 91 nM) for the α1 subunit-containing GABAA receptor. FG 7142 also modulates GABA-induced chloride flux (EC50=137 nM) at GABAA receptors expressing the α1 subunit. FG 7142 increases tyrosine hydroxylation and leads to upregulation of β-adrenergic receptors in mouse cerebral cortex.
UsesFG 7142 is a benzodiazepine inverse agonist anxiogenic compound.
DefinitionChEBI: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.
Biological ActivityInverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex.
Biochem/physiol ActionsBenzodiazepine inverse receptor agonist; potent anxiogenic agent.
storageStore at RT
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Preparation Products And Raw materials
Tag:N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE(78538-74-6) Related Product Information
Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE 9H-PYRIDO[3,4-B]INDOLE ZERENEX E/6026476 N-(4-CHLOROPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE N-(2,4-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE 1-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE 2-([(1-METHYL-9H-BETA-CARBOLIN-3-YL)CARBONYL]AMINO)BENZOIC ACID N-(2,3-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE ZERENEX E/6026463 ZERENEX E/6026469 ZERENEX E/6026461 1-METHYL-N-(2-METHYLPHENYL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE N-(2,5-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE ZERENEX E/6026467 ZERENEX E/6026471