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| | Bromazine Hydrochloride Basic information |
| Product Name: | Bromazine Hydrochloride | | Synonyms: | 2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride;2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethylethylaminehydrochloride;2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethyl-ethylaminhydrochloride;2-(4-bromobenzohydryloxy)-ethyl-dimethylaminehydrochloride;2-(4-bromodiphenylmethoxy)ethyldimethylamine;4-bromo-alpha-phenylbenzyl2-dimethylaminoethylether;ambodrylhydrochloride;beta-(p-bromobenzhydryloxy)ethyldimethylaminehydrochloride | | CAS: | 1808-12-4 | | MF: | C17H21BrClNO | | MW: | 370.71174 | | EINECS: | 2173109 | | Product Categories: | Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 1808-12-4.mol |  |
| | Bromazine Hydrochloride Chemical Properties |
| Melting point | 144-145° | | storage temp. | Refrigerator | | solubility | Acetone (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | Pale Yellow | | BRN | 3754363 |
| | Bromazine Hydrochloride Usage And Synthesis |
| Description | Bromodiphenhydramine is a histamine H1 receptor antagonist. It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 μg/ml. Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats. It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg. | | Uses | Antihistaminic. | | Definition | ChEBI: The hydrochloride salt of bromazine. An antihistamine with antimicrobial properties, it is used in the control of cutaneous allergies. | | Brand name | Ambodryl. | | General Description | Bromodiphenhydraminehydrochloride, 2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine hydrochloride(Ambodryl Hydrochloride), is a white to pale buff crystallinepowder that is freely soluble in water and in alcohol.Relative to diphenhydramine, bromodiphenhydramine ismore lipid soluble and was twice as effective in protectingagainst the lethal effects of histamine aerosols. |
| | Bromazine Hydrochloride Preparation Products And Raw materials |
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